English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
 Local TagsRelease HistoryDetailsSummary
  Medial prefrontal cortex predicts internally driven strategy shifts

Schuck, N. W., Gaschler, R., Wenke, D., Heinzle, J., Frensch, P. A., Haynes, J.-D., et al. (2015). Medial prefrontal cortex predicts internally driven strategy shifts. Neuron, 86(1), 331-340. doi:10.1016/j.neuron.2015.03.015.

Item is

 

show all hide all

Basic

show hide
Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0029-7FE1-2 Version Permalink: https://hdl.handle.net/21.11116/0000-000D-6459-F
Genre: Journal Article

Files

show Files

Locators

show
hide
Locator:
https://doi.org/10.1016/j.neuron.2015.03.015 (Publisher version)
Description:
-
OA-Status:
Green

Creators

show
hide
 Creators:
Schuck, Nicolas W.1, 2, 3, Author
Gaschler, Robert2, 4, Author
Wenke, Dorit2, Author
Heinzle, Jakob5, 6, Author
Frensch, Peter A.2, Author
Haynes, John-Dylan6, 7, 8, Author           
Reverberi, Carlo6, 9, 10, Author
Affiliations:
1Princeton Neuroscience Institute, Princeton University, NJ, USA, ou_persistent22              
2Department of Psychology, Humboldt University Berlin, Germany, ou_persistent22              
3Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany, ou_persistent22              
4Department of Psychology, University Koblenz-Landau, Landau, Germany, ou_persistent22              
5Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich, Switzerland, ou_persistent22              
6Bernstein Center for Computational Neuroscience, Berlin, Germany, ou_persistent22              
7Max Planck Fellow Research Group Attention and Awareness, MPI for Human Cognitive and Brain Sciences, Max Planck Society, Leipzig, DE, ou_634553              
8Department of Neurology, Otto von Guericke University Magdeburg, Germany, ou_persistent22              
9Department of Psychology, University of Milano–Bicocca, Italy, ou_persistent22              
10NeuroMI – Milan Center for Neuroscience, Italy, ou_persistent22              

Content

show
hide
Free keywords: Adult; Attention; Decision Making; Female; Functional Laterality; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Oxygen; Photic Stimulation; Prefrontal Cortex; Reaction Time; ROC Curve; Support Vector Machine; Visual Perception; Young Adult
 Abstract: Many daily behaviors require us to actively focus on the current task and ignore all other distractions. Yet, ignoring everything else might hinder the ability to discover new ways to achieve the same goal. Here, we studied the neural mechanisms that support the spontaneous change to better strategies while an established strategy is executed. Multivariate neuroimaging analyses showed that before the spontaneous change to an alternative strategy, medial prefrontal cortex (MPFC) encoded information that was irrelevant for the current strategy but necessary for the later strategy. Importantly, this neural effect was related to future behavioral changes: information encoding in MPFC was changed only in participants who eventually switched their strategy and started before the actual strategy change. This allowed us to predict spontaneous strategy shifts ahead of time. These findings suggest that MPFC might internally simulate alternative strategies and shed new light on the organization of PFC.

Details

show
hide
Language(s): eng - English
 Dates: 2014-08-182015-03-022015-03-262015-04-08
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.neuron.2015.03.015
PMID: 25819613
PMC: PMC4425426
Other: Epub 2015
 Degree: -

Event

show

Legal Case

show

Project information

show hide
Project name : -
Grant ID : -
Funding program : -
Funding organization : International Max Planck Research School LIFE
Project name : -
Grant ID : R01MH098861
Funding program : -
Funding organization : National Institutes of Health (NIH)
Project name : -
Grant ID : 2010RP5RNM_001
Funding program : -
Funding organization : Ministry of Education, Universities and Research (MIUR)
Project name : -
Grant ID : 01GQ1001C
Funding program : Bernstein Computational Neuroscience Program
Funding organization : German Federal Ministry of Education and Research (BMBF)
Project name : Exc 257 NeuroCure
Grant ID : KFO247, SFB 940, WE 2852/3-1
Funding program : -
Funding organization : German Research Foundation (DFG)

Source 1

show
hide
Title: Neuron
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cambridge, Mass. : Cell Press
Pages: - Volume / Issue: 86 (1) Sequence Number: - Start / End Page: 331 - 340 Identifier: ISSN: 0896-6273
CoNE: https://pure.mpg.de/cone/journals/resource/954925560565