English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Modeling effects of cerebellar and basal ganglia lesions on adaptation and anticipation during sensorimotor synchronization

van der Steen, M. C., Schwartze, M., Kotz, S. A., & Keller, P. E. (2015). Modeling effects of cerebellar and basal ganglia lesions on adaptation and anticipation during sensorimotor synchronization. Annals of the New York Academy of Sciences, 1337, 101-110. doi:10.1111/nyas.12628.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0029-AD9C-D Version Permalink: http://hdl.handle.net/21.11116/0000-0003-798C-8
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
van der Steen, M. C.1, Author              
Schwartze, Michael2, 3, Author              
Kotz, Sonja A.2, 3, Author              
Keller, Peter E.1, 4, Author              
Affiliations:
1Max Planck Research Group Music Cognition and Action, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634555              
2Department Neuropsychology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634551              
3School of Psychological Sciences, University of Manchester, United Kingdom, ou_persistent22              
4The MARCS Institute, University of Western Sydney, Australia, ou_persistent22              

Content

show
hide
Free keywords: Sensorimotor synchronization; Timing; Patients; Computational modeling; Prediction; Error correction
 Abstract: This study addressed the role of subcortical brain structures in temporal adaptation and anticipation during sensorimotor synchronization. The performance of patients with cerebellar or basal ganglia lesions was compared with that of healthy control participants on tasks requiring the synchronization of drum strokes with adaptive and tempo-changing auditory pacing sequences. The precision of sensorimotor synchronization was generally lower in patients relative to controls (i.e., variability of asynchronies was higher in patients), although synchronization accuracy (mean asynchrony) was commensurate. A computational model of adaptation and anticipation (ADAM) was used to examine potential sources of individual differences in precision by estimating participants’ use of error correction, temporal prediction, and the amount of variability associated with central timekeeping and peripheral motor processes. Parameter estimates based on ADAM indicate that impaired precision was attributable to increased variability of timekeeper and motor processes as well as to reduced temporal prediction in both patient groups. Adaptive processes related to continuously applied error correction were, by contrast, intact in patients. These findings highlight the importance of investigating how subcortical structures, including the cerebellum and basal ganglia, interact with a broader network of cortical regions to support temporal adaptation and anticipation during sensorimotor synchronization.

Details

show
hide
Language(s): eng - English
 Dates: 2015-03-132015-03
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1111/nyas.12628
PMID: 25773623
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Annals of the New York Academy of Sciences
  Other : Ann. N.Y. Acad. Sci.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: New York
Pages: - Volume / Issue: 1337 Sequence Number: - Start / End Page: 101 - 110 Identifier: ISSN: 0077-8923
CoNE: /journals/resource/954926958894_2