English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Structural and functional analysis of the RNA helicase Prp43 from the thermophilic eukaryote Chaetomium thermophilum.

Tauchert, M. J., Fourmann, J. B., Christian, H., Lührmann, R., & Ficner, R. (2016). Structural and functional analysis of the RNA helicase Prp43 from the thermophilic eukaryote Chaetomium thermophilum. Acta Crystallographica Section F, 72(2), 112-120. doi:10.1107/S2053230X15024498.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0029-C6DE-2 Version Permalink: http://hdl.handle.net/21.11116/0000-0000-32B8-8
Genre: Journal Article

Files

show Files
hide Files
:
2253003.pdf (Publisher version), 3MB
Name:
2253003.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-
:
2253003_Suppl.pdf (Supplementary material), 444KB
Name:
2253003_Suppl.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Description:
-

Creators

show
hide
 Creators:
Tauchert, M. J., Author
Fourmann, J. B.1, Author              
Christian, H., Author
Lührmann, R.1, Author              
Ficner, R., Author
Affiliations:
1Department of Cellular Biochemistry, MPI for Biophysical Chemistry, Max Planck Society, ou_578576              

Content

show
hide
Free keywords: Spliceosome; RNA helicase; DEAH-box protein; DHX15
 Abstract: RNA helicases are indispensable for all organisms in each domain of life and have implications in numerous cellular processes. The DEAH-box RNA helicase Prp43 is involved in pre-mRNA splicing as well as rRNA maturation. Here, the crystal structure of Chaetomium thermophilum Prp43 at 2.9 angstrom resolution is revealed. Furthermore, it is demonstrated that Prp43 from C. thermophilum is capable of functionally replacing its orthologue from Saccharomyces cerevisiae in spliceosomal disassembly assays.

Details

show
hide
Language(s): eng - English
 Dates: 2016-02-222016-02
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1107/S2053230X15024498
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Acta Crystallographica Section F
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 72 (2) Sequence Number: - Start / End Page: 112 - 120 Identifier: -