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  Nutriproteomics: facts, concepts, and perspectives

Sauer, S., & Luge, T. (2015). Nutriproteomics: facts, concepts, and perspectives. Proteomics, 15(5-6), 997-1013. doi:10.1002/pmic.201400383.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-58BB-5 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-58BC-3
Genre: Journal Article

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Sauer.pdf (Publisher version), 743KB
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2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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 Creators:
Sauer, Sascha1, Author              
Luge, Toni1, Author              
Affiliations:
1Nutrigenomics and Gene Regulation (Sascha Sauer), Independent Junior Research Groups (OWL), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1479662              

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Free keywords: *Computational Biology Mass Spectrometry *Nutritional Sciences Diagnostics Food science Proteogenomics Systems biology
 Abstract: Nutrition is a basic component of life. Nowadays, human nutrition research focuses amongst others on health-related aspects of food ingredients and extracts, and on analyzing the outcomes of specific diets. Usually, food ingredients such as bioactive peptides come in complex matrices. Single compounds, multiple interactions thereof and the underlying food matrix can vary physiological response of the organism. Proteins and peptides derived from food and beverages can cause adverse allergic reactions but are in general required for multiple functions such as growth and homeostatic regulation. Endogenously expressed human proteins and peptides can be used as biomarkers to monitor physiological deregulation and the effects of food consumption. The intestinal microbiome seems to play a fundamental role in establishing and maintaining physiological regulation and in digesting proteins and peptides and other biomolecules derived from food. Notably, the subtle interplay of flavor naturals in food and beverages with olfactory receptors can result in establishing human taste preferences, which again influences overall physiology. This article presents basic approaches and concepts to address scientific questions in nutritional proteomics and discusses potential benefits of proteomics-based methodologies to help advance the field of molecular nutrition research.

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Language(s): eng - English
 Dates: 2015-02-062015-03
 Publication Status: Published in print
 Pages: 17
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1002/pmic.201400383
ISSN: 1615-9861 (Electronic)1615-9853 (Print)
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Title: Proteomics
Source Genre: Journal
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Publ. Info: Weinheim : WILEY-VCH
Pages: - Volume / Issue: 15 (5-6) Sequence Number: - Start / End Page: 997 - 1013 Identifier: ISSN: 1615-9853
CoNE: https://pure.mpg.de/cone/journals/resource/1000000000294310