The UK10K project identifies rare variants in health and disease

Walter, K.; Min, J.L.; Huang, J.; Crooks, L.; Memari, Y.; McCarthy, S.; Perry, J.R.B.; Xu, C.; Futema, M.; Lawson, D.; Iotchkova, V.; Schiffels, Stephan; Hendricks, A.E.; Danecek, P.; Li, R.; Floyd, J.; Wain, L.V.; Barroso, I.; Humphries, S.E.; Hurles, M.E.; Zeggini, E.; Barrett, J.C.; Plagnol, V.; Richards, J.B.; Greenwood, C.M.T.; Timpson, N.J.; Durbin, R.; Bala, S.; Clapham, P.; Coates, G.; Cox, T.; Daly, A.; Du, Y.; Edkins, S.; Ellis, P.; Flicek, P.; Guo, X.; Guo, X.; Huang, L.; Jackson, D.K.; Joyce, C.; Keane, T.; Kolb-Kokocinski, A.; Langford, C.; Li, Y.; Liang, J.; Lin, H.; Liu, R.; Maslen, J.; Muddyman, D.; Quail, M.A.; Stalker, J.; Sun, J.; Tian, J.; Wang, G.; Wang, J.; Wang, Y.; Wong, K.; Zhang, P.; Birney, E.; Boustred, C.; Chen, L.; Clement, G.; Cocca, M.; Smith, G.D.; Day, I.N.M.; Day-Williams, A.; Down, T.; Dunham, I.; Evans, D.M.; Gaunt, T.R.; Geihs, M.; Hart, D.; Howie, B.; Hubbard, T.; Hysi, P.; Jamshidi, Y.; Karczewski, K.J.; Kemp, J.P.; Lachance, G.; Lek, M.; Lopes, M.; MacArthur, D.G.; Marchini, J.; Mangino, M.; Mathieson, I.; Metrustry, S.; Moayyeri, A.; Northstone, K.; Panoutsopoulou, K.; Paternoster, L.; Quaye, L.; Ring, S.; Ritchie, G.R.S.; Shihab, H.A.; Shin, S.-Y.; Small, K.S.; Artigas, M.S.; Soranzo, N.; Southam, L.; Spector, T.D.; St Pourcain, B.; Surdulescu, G.; Tachmazidou, I.; Tobin, M.D.; Valdes, A.M.; Visscher, P.M.; Ward, K.; Wilson, S.G.; Yang, J.; Zhang, F.; Zheng, H.-F.; Anney, R.; Ayub, M.; Blackwood, D.; Bolton, P.F.; Breen, G.; Collier, D.A.; Craddock, N.; Curran, S.; Curtis, D.; Gallagher, L.; Geschwind, D.; Gurling, H.; Holmans, P.; Lee, I.; Lönnqvist, J.; McGuffin, P.; McIntosh, A.M.; McKechanie, A.G.; McQuillin, A.; Morris, J.; O'Donovan, M.C.; Owen, M.J.; Palotie, A.; Parr, J.R.; Paunio, T.; Pietilainen, O.; Rehnström, K.; Sharp, S.I.; Skuse, D.; St Clair, D.; Suvisaari, J.; Walters, J.T.R.; Williams, H.J.; Bochukova, E.; Bounds, R.; Dominiczak, A.; Farooqi, I.S.; Keogh, J.; Marenne, G.; Morris, A.; O'Rahilly, S.; Porteous, D.J.; Smith, B.H.; Wheeler, E.; Al Turki, S.; Anderson, C.A.; Antony, D.; Beales, P.; Bentham, J.; Bhattacharya, S.; Calissano, M.; Carss, K.; Chatterjee, K.; Cirak, S.; Cosgrove, C.; Fitzpatrick, D.R.; Foley, A.R.; Franklin, C.S.; Grozeva, D.; Mitchison, H.M.; Muntoni, F.; Onoufriadis, A.; Parker, V.; Payne, F.; Raymond, F.L.; Roberts, N.; Savage, D.B.; Scambler, P.; Schmidts, M.; Schoenmakers, N.; Semple, R.K.; Serra, E.; Spasic-Boskovic, O.; Stevens, E.; Van Kogelenberg, M.; Vijayarangakannan, P.; Williamson, K.A.; Wilson, C.; Whyte, T.; Ciampi, A.; Oualkacha, K.; Bobrow, M.; Griffin, H.; Kaye, J.; Kennedy, K.; Kent, A.; Smee, C.; Charlton, R.; Ekong, R.; Khawaja, F.; Lopes, L.R.; Migone, N.; Payne, S.J.; Pollitt, R.C.; Povey, S.; Ridout, C.K.; Robinson, R.L.; Scott, R.H.; Shaw, A.; Syrris, P.; Taylor, R.; Vandersteen, A.M.; Amuzu, A.; Casas, J.P.; Chambers, J.C.; Dedoussis, G.; Gambaro, G.; Gasparini, P.; Isaacs, A.; Johnson, J.; Kleber, M.E.; Kooner, J.S.; Langenberg, C.; Luan, J.; Malerba, G.; März, W.; Matchan, A.; Morris, R.; Nordestgaard, B.G.; Benn, M.; Scott, R.A.; Toniolo, D.; Traglia, M.; Tybjaerg-Hansen, A.; Van Duijn, C.M.; Van Leeuwen, E.M.; Varbo, A.; Whincup, P.; Zaza, G.; Zhang, W.

doi:10.1038/nature14962

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The UK10K project identifies rare variants in health and disease

Walter, K., Min, J., Huang, J., Crooks, L., Memari, Y., McCarthy, S., et al. (2015). The UK10K project identifies rare variants in health and disease. Nature, 526(7571), 82-89. doi:10.1038/nature14962.

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Creators:
Walter, K.¹, Author
Min, J.L., Author
Huang, J., Author
Crooks, L., Author
Memari, Y., Author
McCarthy, S., Author
Perry, J.R.B., Author
Xu, C., Author
Futema, M., Author
Lawson, D., Author
Iotchkova, V., Author
Schiffels, Stephan², Author
Hendricks, A.E., Author
Danecek, P., Author
Li, R., Author
Floyd, J., Author
Wain, L.V., Author
Barroso, I., Author
Humphries, S.E., Author
Hurles, M.E., Author
Zeggini, E., AuthorBarrett, J.C., AuthorPlagnol, V., AuthorRichards, J.B., AuthorGreenwood, C.M.T., AuthorTimpson, N.J., AuthorDurbin, R., AuthorBala, S., Author         Clapham, P., AuthorCoates, G., AuthorCox, T., AuthorDaly, A., AuthorDu, Y., AuthorEdkins, S., AuthorEllis, P., AuthorFlicek, P., AuthorGuo, X.³, Author         Guo, X.³, Author         Huang, L., AuthorJackson, D.K., AuthorJoyce, C., AuthorKeane, T., AuthorKolb-Kokocinski, A., AuthorLangford, C., AuthorLi, Y.⁴, Author         Liang, J., AuthorLin, H., AuthorLiu, R.⁵, Author         Maslen, J., AuthorMuddyman, D., AuthorQuail, M.A., AuthorStalker, J., AuthorSun, J., AuthorTian, J., AuthorWang, G.⁶, Author         Wang, J.⁷, Author         Wang, Y.⁸, Author         Wong, K., AuthorZhang, P., AuthorBirney, E., AuthorBoustred, C., AuthorChen, L.⁹, Author         Clement, G., AuthorCocca, M., AuthorSmith, G.D., AuthorDay, I.N.M., AuthorDay-Williams, A., AuthorDown, T., AuthorDunham, I., AuthorEvans, D.M., AuthorGaunt, T.R., AuthorGeihs, M., AuthorHart, D., AuthorHowie, B., AuthorHubbard, T., AuthorHysi, P., AuthorJamshidi, Y., AuthorKarczewski, K.J., AuthorKemp, J.P., AuthorLachance, G., AuthorLek, M., AuthorLopes, M., AuthorMacArthur, D.G., AuthorMarchini, J., AuthorMangino, M., AuthorMathieson, I., AuthorMetrustry, S., AuthorMoayyeri, A., AuthorNorthstone, K., AuthorPanoutsopoulou, K., AuthorPaternoster, L., AuthorQuaye, L., AuthorRing, S., AuthorRitchie, G.R.S., AuthorShihab, H.A., AuthorShin, S.-Y., AuthorSmall, K.S., AuthorArtigas, M.S., AuthorSoranzo, N., AuthorSoutham, L., AuthorSpector, T.D., AuthorSt Pourcain, B., AuthorSurdulescu, G., AuthorTachmazidou, I., AuthorTobin, M.D., AuthorValdes, A.M., AuthorVisscher, P.M., AuthorWard, K., AuthorWilson, S.G., AuthorYang, J., Author         Zhang, F.^{10, 11}, Author         Zheng, H.-F., AuthorAnney, R., AuthorAyub, M., AuthorBlackwood, D., AuthorBolton, P.F., AuthorBreen, G., AuthorCollier, D.A., AuthorCraddock, N., AuthorCurran, S., AuthorCurtis, D., AuthorGallagher, L., AuthorGeschwind, D., AuthorGurling, H., AuthorHolmans, P., AuthorLee, I., AuthorLönnqvist, J., AuthorMcGuffin, P., AuthorMcIntosh, A.M., AuthorMcKechanie, A.G., AuthorMcQuillin, A., AuthorMorris, J., AuthorO'Donovan, M.C., AuthorOwen, M.J., AuthorPalotie, A., AuthorParr, J.R., AuthorPaunio, T., AuthorPietilainen, O., AuthorRehnström, K., AuthorSharp, S.I., AuthorSkuse, D., AuthorSt Clair, D., AuthorSuvisaari, J., AuthorWalters, J.T.R., AuthorWilliams, H.J., AuthorBochukova, E., AuthorBounds, R., AuthorDominiczak, A., AuthorFarooqi, I.S., AuthorKeogh, J., AuthorMarenne, G., AuthorMorris, A., AuthorO'Rahilly, S., AuthorPorteous, D.J., AuthorSmith, B.H., AuthorWheeler, E., AuthorAl Turki, S., AuthorAnderson, C.A., AuthorAntony, D., AuthorBeales, P., AuthorBentham, J., AuthorBhattacharya, S.¹², Author         Calissano, M., AuthorCarss, K., AuthorChatterjee, K., AuthorCirak, S., AuthorCosgrove, C., AuthorFitzpatrick, D.R., AuthorFoley, A.R., AuthorFranklin, C.S., AuthorGrozeva, D., AuthorMitchison, H.M., AuthorMuntoni, F., AuthorOnoufriadis, A., AuthorParker, V., AuthorPayne, F., AuthorRaymond, F.L., AuthorRoberts, N.¹³, Author         Savage, D.B., AuthorScambler, P., AuthorSchmidts, M., AuthorSchoenmakers, N., AuthorSemple, R.K., AuthorSerra, E., AuthorSpasic-Boskovic, O., AuthorStevens, E., AuthorVan Kogelenberg, M., AuthorVijayarangakannan, P., AuthorWilliamson, K.A., AuthorWilson, C., AuthorWhyte, T., AuthorCiampi, A., AuthorOualkacha, K., AuthorBobrow, M., AuthorGriffin, H., AuthorKaye, J., AuthorKennedy, K., AuthorKent, A., AuthorSmee, C., AuthorCharlton, R., AuthorEkong, R., AuthorKhawaja, F., AuthorLopes, L.R., AuthorMigone, N., AuthorPayne, S.J., AuthorPollitt, R.C., AuthorPovey, S., AuthorRidout, C.K., AuthorRobinson, R.L., AuthorScott, R.H., AuthorShaw, A., AuthorSyrris, P., AuthorTaylor, R., AuthorVandersteen, A.M., AuthorAmuzu, A., AuthorCasas, J.P., AuthorChambers, J.C., AuthorDedoussis, G., AuthorGambaro, G., AuthorGasparini, P., AuthorIsaacs, A., AuthorJohnson, J., AuthorKleber, M.E., AuthorKooner, J.S., AuthorLangenberg, C., AuthorLuan, J., AuthorMalerba, G., AuthorMärz, W., AuthorMatchan, A., AuthorMorris, R., AuthorNordestgaard, B.G., AuthorBenn, M., AuthorScott, R.A., AuthorToniolo, D., AuthorTraglia, M., AuthorTybjaerg-Hansen, A., AuthorVan Duijn, C.M., AuthorVan Leeuwen, E.M., AuthorVarbo, A., AuthorWhincup, P., AuthorZaza, G., AuthorZhang, W., Author          more..

Affiliations:
1Department of NMR Based Structural Biology, MPI for biophysical chemistry, Max Planck Society, ou_578567
2External Organizations, ou_persistent22
3Computational Biology and Applied Algorithmics, MPI for Informatics, Max Planck Society, ou_40046
4ADIS, MPI for Plant Breeding Research, Max Planck Society, ou_1113564
5Shanghai Univ, Sch Environm & Chem Engn, Shanghai 200444, Peoples R China, ou_persistent22
6Dept. of Plant Breeding and Genetics (Maarten Koornneef), MPI for Plant Breeding Research, Max Planck Society, ou_1113569
7Department of Biochemistry and Cell Biology, MPI for biophysical chemistry, Max Planck Society, ou_578618
8Dept. of Plant Microbe Interactions (Paul Schulze-Lefert), MPI for Plant Breeding Research, Max Planck Society, ou_1113572
9Department of Dynamics at Surfaces, MPI for Biophysical Chemistry, Max Planck Society, ou_578600
10Department 'Resilience and Transformation in Eurasia', MPI for Social Anthropology, Max Planck Society, ou_907576
11Department II, MPI for Social Anthropology, Max Planck Society, ou_907576
12Algorithms and Complexity, MPI for Informatics, Max Planck Society, ou_24019
13Religious Diversity, MPI for the Study of Religious and Ethnic Diversity, Max Planck Society, ou_1116554

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Language(s): eng - English

Dates: Submitted: 2015-03-15Accepted: 2015-07-17Published Online: 2015-09-14Date issued: 2015-10-01

Publication Status: Issued

Pages: 21

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Table of Contents: -

Rev. Type: Peer

Identifiers: DOI: 10.1038/nature14962
BibTex Citekey: Walter201582
Other: shh421

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Title: Nature

Abbreviation : Nature

Source Genre: Journal

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Publ. Info: London : Nature Publishing Group

Pages: - Volume / Issue: 526 (7571) Sequence Number: - Start / End Page: 82 - 89 Identifier: ISSN: 0028-0836
CoNE: https://pure.mpg.de/cone/journals/resource/954925427238