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  Two-photon imaging to a depth of 1000 µm microm in living brains by use of a Ti:Al2O3 regenerative amplifier

Theer, P., Hasan, M. T., & Denk, W. (2003). Two-photon imaging to a depth of 1000 µm microm in living brains by use of a Ti:Al2O3 regenerative amplifier. Optics Letters, 28(12), 1022-1024. doi:10.1364/OL.28.001022.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-1179-A Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-117A-8
Genre: Journal Article
Alternative Title : Two-photon imaging to a depth of 1000 µm microm in living brains by use of a Ti:Al2O3 regenerative amplifier

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OptLett_28_2003_1022.pdf (Any fulltext), 3MB
 
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 Creators:
Theer, Patrick1, Author              
Hasan, Mazahir T.1, 2, Author              
Denk, Winfried1, Author              
Affiliations:
1Department of Biomedical Optics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497699              
2Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              

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Free keywords: Lasers and laser optics : Optical amplifiers; Medical optics and biotechnology : Turbid media; Fluorescence microscopy; Microscopy : Scanning microscopy; Microscopy : Three-dimensional microscopy; Nonlinear optics : Multiphoton processes
 Abstract: It is shown that two-photon fluorescence images can be obtained throughout almost the entire gray matter of the mouse neocortex by using optically amplified femtosecond pulses. The achieved imaging depth approaches the theoretical limit set by excitation of out-of-focus fluorescence.

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Language(s): eng - English
 Dates: 2002-12-202003-06-152003-06-15
 Publication Status: Published in print
 Pages: 3
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
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Title: Optics Letters
Source Genre: Journal
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Publ. Info: Washington : Optical Society of America
Pages: - Volume / Issue: 28 (12) Sequence Number: - Start / End Page: 1022 - 1024 Identifier: ISSN: 0146-9592
CoNE: https://pure.mpg.de/cone/journals/resource/954925474435