English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Whisker movements evoked by stimulation of single pyramidal cells in rat motor cortex

Brecht, M., Schneider, M., Sakmann, B., & Margrie, T. W. (2004). Whisker movements evoked by stimulation of single pyramidal cells in rat motor cortex. Nature, 427(6976), 704-710. doi:10.1038/nature02266.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-14DD-0 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-14E1-4
Genre: Journal Article
Alternative Title : Whisker movements evoked by stimulation of single pyramidal cells in rat motor cortex

Files

show Files
hide Files
:
Nature_427_2004_704.pdf (Any fulltext), 633KB
 
File Permalink:
-
Name:
Nature_427_2004_704.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute for Medical Research, MHMF; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Description:
-
Locator:
https://dx.doi.org/10.1038/nature02266 (Any fulltext)
Description:
-

Creators

show
hide
 Creators:
Brecht, Michael1, Author              
Schneider, Miriam1, Author              
Sakmann, Bert1, Author              
Margrie, Troy W.1, 2, Author              
Affiliations:
1Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497701              
2Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              

Content

show
hide
Free keywords: -
 Abstract: Neuronal activity in the motor cortex is understood to be correlated with movements, but the impact of action potentials (APs) in single cortical neurons on the generation of movement has not been fully determined. Here we show that trains of APs in single pyramidal cells of rat motor cortex can evoke long sequences of small whisker movements. For layer-5 pyramids, we find that evoked rhythmic movements have a constant phase relative to the AP train, indicating that single layer-5 pyramids can reset the rhythm of whisker movements. Action potentials evoked in layer-6 pyramids can generate bursts of rhythmic whisking, with a variable phase of movements relative to the AP train. An increasing number of APs decreases the latency to onset of movement, whereas AP frequency determines movement direction and amplitude. We find that the efficacy of cortical APs in evoking whisker movements is not dependent on background cortical activity and is greatly enhanced in waking rats. We conclude that in vibrissae motor cortex sparse AP activity can evoke movements.

Details

show
hide
Language(s): eng - English
 Dates: 2003-07-012003-12-032004-02-19
 Publication Status: Published in print
 Pages: 7
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Nature
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: London : Nature Publishing Group
Pages: - Volume / Issue: 427 (6976) Sequence Number: - Start / End Page: 704 - 710 Identifier: ISSN: 0028-0836
CoNE: https://pure.mpg.de/cone/journals/resource/954925427238