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  Miniaturized two-photon microscope based on a flexible coherent fiber bundle and a gradient-index lens objective

Göbel, W., Kerr, J., Nimmerjahn, A., & Helmchen, F. (2004). Miniaturized two-photon microscope based on a flexible coherent fiber bundle and a gradient-index lens objective. Optics Letters, 29(21), 2521-2523. doi:10.1364/OL.29.002521.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-18EF-6 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-18F2-9
Genre: Journal Article
Alternative Title : Miniaturized two-photon microscope based on a flexible coherent fiber bundle and a gradient-index lens objective

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OptLett_29_2004_2521.pdf (Any fulltext), 863KB
 
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http://dx.doi.org/10.1364/OL.29.002521 (Any fulltext)
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 Creators:
Göbel, Werner, Author
Kerr, Jason1, 2, Author              
Nimmerjahn, Axel1, Author              
Helmchen, Fritjof1, Author              
Affiliations:
1Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497701              
2Department of Biomedical Optics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497699              

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 Abstract: We present a miniature, flexible two-photon microscope consisting of a fused coherent optical fiber bundle with 30,000 cores and a gradient-index lens objective. The laser focus of a standard two-photon laser-scanning microscope was scanned over the entrance surface of the fiber bundle, resulting in sequential coupling into individual cores. Fluorescent light was detected through the fiber bundle. Micrometer-sized fluorescent beads and pollen grains were readily resolved. In addition, fluorescently labeled blood vessels were imaged through the fiber bundle in rat brain in vivo.

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Language(s): eng - English
 Dates: 2004-06-022004-11-01
 Publication Status: Published in print
 Pages: 3
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Degree: -

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Title: Optics Letters
Source Genre: Journal
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Publ. Info: Washington : Optical Society of America
Pages: - Volume / Issue: 29 (21) Sequence Number: - Start / End Page: 2521 - 2523 Identifier: ISSN: 0146-9592
CoNE: https://pure.mpg.de/cone/journals/resource/954925474435