English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  A proof theoretic view of spatial and temporal dependencies in biochemical systems

Olarte, C., Chiarugi, D., Falaschi, M., & Hermith, D. (2016). A proof theoretic view of spatial and temporal dependencies in biochemical systems. Theoretical Computer Science, 641, 25-42. doi:10.1016/j.tcs.2016.03.029.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-33F5-2 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-BD2D-2
Genre: Journal Article

Files

show Files
hide Files
:
2263219.pdf (Publisher version), 780KB
 
File Permalink:
-
Name:
2263219.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute of Colloids and Interfaces, MTKG; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-
:
Manuskript.pdf (Any fulltext), 481KB
 
File Permalink:
-
Name:
Manuskript.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute of Colloids and Interfaces, MTKG; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Olarte, C., Author
Chiarugi, D.1, Author              
Falaschi, M., Author
Hermith, D., Author
Affiliations:
1Angelo Valleriani, Theorie & Bio-Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863324              

Content

show
hide
Free keywords: Biochemical systems; Linear logic; Spatial and temporal modalities; Verification of P systems
 Abstract: The behaviour of biochemical systems such as metabolic and signaling pathways may depend on either the location of the reactants or on the time needed for a reaction to occur. In this paper we propose a formalism for specifying and verifying properties of biochemical systems that combines, coherently, temporal and spatial modalities. To this aim, we consider a fragment of intuitionistic linear logic with subexponentials (SELL). The subexponential signature allows us to capture the spatial relations among the different components of the system and the timed constraints. We illustrate our approach by specifying some well-known biological systems and verifying properties of them. Moreover, we show that our framework is general enough to give a logic-based semantics to P systems. We show that the proposed logical characterizations has a strong level of adequacy. Hence, derivations in \SELL\ follow exactly the behavior of the modeled system.

Details

show
hide
Language(s):
 Dates: 2016-04-042016-08-16
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1016/j.tcs.2016.03.029
BibTex Citekey: Olarte2016
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Theoretical Computer Science
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Amsterdam : Elsevier
Pages: - Volume / Issue: 641 Sequence Number: - Start / End Page: 25 - 42 Identifier: ISSN: 0304-3975