English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Fiber types of the intrinsic whisker muscle and whisking behavior

Jin, T.-E., Witzemann, V., & Brecht, M. (2004). Fiber types of the intrinsic whisker muscle and whisking behavior. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience, 24(13), 3386-3393. doi:10.1523/JNEUROSCI.5151-03.2004.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-2A65-9 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-2A66-7
Genre: Journal Article
Alternative Title : Fiber types of the intrinsic whisker muscle and whisking behavior

Files

show Files
hide Files
:
JNeurosci_24_2004_3386.pdf (Any fulltext), 671KB
 
File Permalink:
-
Name:
JNeurosci_24_2004_3386.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute for Medical Research, MHMF; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Description:
-
Description:
-

Creators

show
hide
 Creators:
Jin, Tae-Eun1, Author              
Witzemann, Veit1, 2, Author              
Brecht, Michael1, Author              
Affiliations:
1Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497701              
2Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              

Content

show
hide
Free keywords: whisker; vibrissas; whisking; muscle fiber; barrel cortex; myosin heavy chain
 Abstract: Some rodent species show rhythmic bouts of vibrissal protractions and retractions, referred to as whisking, that are among the fastest movements performed by mammals. To better understand the muscular basis of whisking, we compared (1) whisker movements of two whisking species (mouse, rat) and a non-whisking species (guinea pig), (2) the muscle fiber composition of intrinsic whisker muscles of whisking and a non-whisking species, and (3) the muscle fiber composition of intrinsic whisker muscles and of selected skeletal muscles. Using high-speed videography, we found that mice, rats, and guinea pigs can generate fast and large-amplitude whisker movements. Guinea pigs do not show bouts of fast, strictly rhythmic whisker movements, and the average speed of their whisker movements is much lower than in mice and rats. Analysis of mRNA expression of myosin heavy chain isoforms, myofibrillar ATPase staining, and antibody labeling indicate that in all three species intrinsic whisker muscles are composed predominantly of type 2B muscle fibers. Intrinsic whisker muscles of mice consisted of type 2B (> or =90%) and type 2D fibers. In rats we observed, in addition to type 2B/2D fibers, approximately 10% of slow type 1 fibers, and in guinea pigs we observed approximately 3% of slow type 1 fibers and 20% of type 2A fibers. Type 2B fibers have high levels of anaerobic glycolytic enzymes providing a rapid source of ATP and high maximum velocity of contraction but are less fatigue resistant than other muscle fiber types. The high percentage of type 2B fibers distinguishes the intrinsic whisker musculature from skeletal muscles and may have evolved for fast scanning of the sensory environment.

Details

show
hide
Language(s): eng - English
 Dates: 2004-02-252003-11-212004-02-252004-03-31
 Publication Status: Published in print
 Pages: 8
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
  Other : J. Neurosci.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Baltimore, MD : The Society
Pages: - Volume / Issue: 24 (13) Sequence Number: - Start / End Page: 3386 - 3393 Identifier: ISSN: 0270-6474
CoNE: https://pure.mpg.de/cone/journals/resource/954925502187_1