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  Map the light-driven fMRI signal in combination with in vivo recording

Wang, M., He, Y., Tang, Y., Balla, D., Qian, C., & Yu, X. (2015). Map the light-driven fMRI signal in combination with in vivo recording. Poster presented at 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015), Toronto, Canada.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002A-45ED-0 Version Permalink: https://hdl.handle.net/21.11116/0000-0006-9B87-3
Genre: Poster

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http://www.ismrm.org/15/program_files/WedTP03.htm (Publisher version)
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 Creators:
Wang, M1, 2, Author           
He, Y1, 2, Author           
Tang, Y1, 2, Author           
Balla, DZ1, 3, 4, Author           
Qian, C, Author
Yu, X1, 2, Author           
Affiliations:
1Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              
2Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528695              
3Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
4Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

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 Abstract: It remains ambiguous how the direct fiber optic insertion affects the local fMRI signal by optical stimulation. The fiber optic was inserted to target the deep layer cortex expressing Channelrhodopsin 2(ChR2). Robust fMRI signal was detected in the cortical regions close to the fiber tip with varied light pulse parameters on frequency, pulse duration and power level. The light evoked local field potential was also recorded by electrodes inserted into the cortex expressing ChR2. This work provides us a robust light-driven fMRI platform in combination with in vivo recording, which will facilitate the study to decipher cellular contribution to fMRI signal from the local neurovascular network.

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 Dates: 2015-06
 Publication Status: Issued
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 Identifiers: URI: http://www.ismrm.org/15/program_files/WedTP03.htm
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Title: 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015)
Place of Event: Toronto, Canada
Start-/End Date: 2015-05-30 - 2015-06-05

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Title: 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 2117 Start / End Page: - Identifier: -