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  Laminar Differences in Neural Activity During Positive and Negative Bold Conditions

Zaldivar, D., Logothetis, N., & Goense, J. (2015). Laminar Differences in Neural Activity During Positive and Negative Bold Conditions. In 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015).

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002A-4612-3 Version Permalink: https://hdl.handle.net/21.11116/0000-0006-9B92-6
Genre: Meeting Abstract

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http://www.ismrm.org/15/program_files/TueSci07.htm (Publisher version)
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 Creators:
Zaldivar, D1, 2, Author           
Logothetis, NK1, 2, Author           
Goense, J1, 2, Author           
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: There is still debate whether negative BOLD responses have a neural or vascular origin. Laminar differences in neurovascular coupling have also been observed during the negative-BOLD response. We investigated whether these differences have a neural origin by performing laminar recordings in V1. We positioned two laminar electrodes in V1; one of these was located in the negative-BOLD area whereas the other in the positive-BOLD area. We observed that the middle cortical layers did not decrease their neural activity while all other layers did, suggesting that the negative BOLD response is driven by the neural activity reductions in the supragranular and infragranular layers.

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 Dates: 2015-06
 Publication Status: Issued
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 Identifiers: BibTex Citekey: ZaldivarLG2015
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Title: 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015)
Place of Event: Toronto, Canada
Start-/End Date: 2015-05-30 - 2015-06-05

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Title: 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 0357 Start / End Page: - Identifier: -