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Discovery of ‘TUF’ DNA – unusually difficult to denature stretches of genomic DNA sequence.
Enrichment methods – new methods, benchmarking and descriptors of enrichment technologies.
Manipulating, visualizing and interrogating individual DNA molecules in nanosystems.
Nanopore Sequencing – first commercial nanopore sequencer from Oxford Nanopore Technologies.
Abstract:
e REvolutionary Approaches and Devices for Nucleic Acid analysis (READNA) project received funding from the European Commission for 41/2 years. The objectives of the project revolved around technological developments in nucleic acid analysis. The project partners have discovered, created and developed a huge body of insights into nucleic acid analysis, ranging from improvements and implementation of current technologies to the most promising sequencing technologies that constitute a 3(rd) and 4(th) generation of sequencing methods with nanopores and in situ sequencing, respectively.