English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  The Catalytic Asymmetric Fischer Indolization

Müller, S., Webber, M. J., & List, B. (2011). The Catalytic Asymmetric Fischer Indolization. Journal of the American Chemical Society, 133(46), 18534-18537. doi:10.1021/ja2092163.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Müller, Steffen1, Author              
Webber, Matthew J.1, Author              
List, Benjamin1, Author              
Affiliations:
1Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445585              

Content

show
hide
Free keywords: -
 Abstract: The first catalytic asymmetric Fischer indolization is reported. In the presence of a 5 mol % loading of a novel spirocyclic chiral phosphoric acid, 4-substituted cyclohexanone-derived phenylhydrazones undergo a highly enantioselective indolization. Efficient catalyst turnover was achieved by the addition of a weakly acidic cation exchange resin, which removes the generated ammonia. The reaction can be conducted under mild conditions and gives various 3-substituted tetrahydrocarbazoles in generally high yields.

Details

show
hide
Language(s): eng - English
 Dates: 2011-08-052011-11-012011-11-23
 Publication Status: Published in print
 Pages: 4
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1021/ja2092163
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Journal of the American Chemical Society
  Other : JACS
  Abbreviation : J. Am. Chem. Soc.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Washington, DC : American Chemical Society
Pages: - Volume / Issue: 133 (46) Sequence Number: - Start / End Page: 18534 - 18537 Identifier: ISSN: 0002-7863
CoNE: https://pure.mpg.de/cone/journals/resource/954925376870