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  Simple convergent-nozzle aerosol injector for single-particle diffractive imaging with X-ray free-electron lasers

Kirian, R. A., Awel, S., Eckerskorn, N., Fleckenstein, H., Wiedorn, M., Adriano, L., et al. (2015). Simple convergent-nozzle aerosol injector for single-particle diffractive imaging with X-ray free-electron lasers. Structural Dynamics, 2(4): 041717. doi:10.1063/1.4922648.

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© R. A. Kirian et al.

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http://dx.doi.org/10.1063/1.4922648 (Publisher version)
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 Creators:
Kirian, R. A.1, 2, Author
Awel, S.1, 3, Author
Eckerskorn, N.4, Author
Fleckenstein, H.1, Author
Wiedorn, M.1, 5, Author
Adriano, L.6, Author
Bajt, S.6, Author
Barthelmess, M.1, Author
Bean, R.7, Author
Beyerlein, K. R.1, Author
Chavas, L. M. G.1, Author
Domaracky, M.1, 8, Author
Heymann, M.1, Author
Horke, D. A.1, Author
Knoska, J.1, 5, Author
Metz, M.1, 5, Author
Morgan, A.1, Author
Oberthuer, D.1, Author
Roth, N.1, Author
Sato, T.1, Author
Paulraj, Lourdu Xavier1, 5, 9, Author              Yefanov, O.1, AuthorRode, A. V.4, AuthorKüpper, J.1, 3, 5, AuthorChapman, H. N.1, 3, 5, Author more..
Affiliations:
1Center for Free-Electron Laser Science, DESY, 22607 Hamburg, Germany, ou_persistent22              
2Department of Physics, Arizona State University, Tempe, Arizona 85287, USA, ou_persistent22              
3Center for Ultrafast Imaging, University of Hamburg, 22761 Hamburg, Germany, ou_persistent22              
4Laser Physics Centre, Research School of Physics and Engineering, Australian National University, Canberra, Australia, ou_persistent22              
5Department of Physics, University of Hamburg, 22761 Hamburg, Germany, ou_persistent22              
6Deutsches Elektronen-Synchrotron DESY, 22607 Hamburg, Germany, ou_persistent22              
7European XFEL GmbH, 22761 Hamburg, Germany, ou_persistent22              
8Faculty of Science, Pavol Jozef Šafárik University in Košice, Slovakia, ou_persistent22              
9International Max Planck Research School for Ultrafast Imaging & Structural Dynamics (IMPRS-UFAST), Max Planck Institute for the Structure and Dynamics of Matter, Max Planck Society, ou_2266714              

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Free keywords: X-ray diffraction; Fluid drops; Aerodynamics; Aerosols; Atmospheric pressure
 Abstract: A major challenge in high-resolution x-ray free-electron laser-based coherent diffractive imaging is the development of aerosol injectors that can efficiently deliver particles to the peak intensity of the focused X-ray beam. Here, we consider the use of a simple convergent-orifice nozzle for producing tightly focused beams of particles. Through optical imaging we show that 0.5 μm particles can be focused to a full-width at half maximum diameter of 4.2 μm, and we demonstrate the use of such a nozzle for injecting viruses into a micro-focused soft-X-ray FEL beam.

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Language(s): eng - English
 Dates: 2015-03-312015-05-182015-06-19
 Publication Status: Published online
 Pages: 12
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1063/1.4922648
 Degree: -

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Title: Structural Dynamics
Source Genre: Journal
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Publ. Info: Melville, NY : American Institute of Physics
Pages: - Volume / Issue: 2 (4) Sequence Number: 041717 Start / End Page: - Identifier: Other: 2329-7778
CoNE: https://pure.mpg.de/cone/journals/resource/2329-7778