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Tuberculosis is still a major health issue and the number one killer of all contagious diseases. But while more than 2 billion people are infected with the tuberculosis agent, only 10% develop an active disease. Current diagnostic tests cannot distinguish between infected people and people with active tuberculosis. In this video, STEFAN H. E. KAUFMANN explains that they found a characteristic gene expression profile of people infected with tuberculosis. Relying on only four markers they developed a highly sensitive method that is not only able to identify people with active tuberculosis but is also suitable for point of care application in countries with low resources.
