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  Coat/tether interactions-exception or rule?

Schröter, S., Beckmann, S., & Schmitt, H. D. (2016). Coat/tether interactions-exception or rule? Frontiers in Cell and Developmental Biology, 4: 44. doi:10.3389/fcell.2016.00044.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-DBE5-4 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-1A5F-6
Genre: Journal Article

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 Creators:
Schröter, S.1, Author              
Beckmann, S.1, Author              
Schmitt, H. D.1, Author              
Affiliations:
1Research Group of Membrane Transport in Yeast, MPI for Biophysical Chemistry, Max Planck Society, ou_578597              

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Free keywords: Coat complexes; Coated vesicles; Protocoatomer; Tethering complex; Vesicle trafficking
 Abstract: Coat complexes are important for cargo selection and vesicle formation. Recent evidence suggests that they may also be involved in vesicle targeting. Tethering factors, which form an initial bridge between vesicles and the target membrane, may bind to coat complexes. In this review, we ask whether these coat/tether interactions share some common mechanisms, or whether they are special adaptations to the needs of very specific transport steps. We compare recent findings in two multisubunit tethering complexes, the Dsl1 complex and the HOPS complex, and put them into context with the TRAPP I complex as a prominent example for coat/tether interactions. We explore where coat/tether interactions are found, compare their function and structure, and comment on a possible evolution from a common ancestor of coats and tethers.

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Language(s): eng - English
 Dates: 2016-05-17
 Publication Status: Published online
 Pages: -
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 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.3389/fcell.2016.00044
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Title: Frontiers in Cell and Developmental Biology
Source Genre: Journal
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Pages: 12 Volume / Issue: 4 Sequence Number: 44 Start / End Page: - Identifier: -