English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Expression of myosin heavy and light chains and phosphorylation of the phosphorylatable myosin light chain in the heart ventricle of the European hamster during hibernation and in summer

Morano, I., Adler, K., Agostini, B., & Hasselbach, W. (1992). Expression of myosin heavy and light chains and phosphorylation of the phosphorylatable myosin light chain in the heart ventricle of the European hamster during hibernation and in summer. Journal of Muscle Research and Cell Motility, 13(1), 64-70. doi:10.1007/BF01738429.

Item is

Files

show Files
hide Files
:
JMuscleResCellMotil_13_1992_64.pdf (Any fulltext), 909KB
 
File Permalink:
-
Name:
JMuscleResCellMotil_13_1992_64.pdf
Description:
-
OA-Status:
Visibility:
Restricted (Max Planck Institute for Medical Research, MHMF; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Description:
-
OA-Status:
Locator:
https://dx.doi.org/10.1007/BF01738429 (Any fulltext)
Description:
-
OA-Status:

Creators

show
hide
 Creators:
Morano, I., Author
Adler, K., Author
Agostini, Bruno1, Author           
Hasselbach, Wilhelm2, Author           
Affiliations:
1Department of Biomedical Optics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497699              
2Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497712              

Content

show
hide
Free keywords: Light Chain; ATPase Activity; Heavy Chain; Myosin Heavy Chain; Myosin Light Chain
 Abstract: We investigated the expression of myosin subunits (myosin heavy chains) as well as light chains and the in vivo phosphorylation of the phosphorylatable myosin light chain in the heart ventricle of the adult male European hamster (Cricetus cricetus L.). Two myosin heavy chain isoenzymes could be detected under native and denaturing electrophoretic conditions having high (alpha-myosin heavy chain) and low (beta-myosin heavy chain) enzymatic activity. Enzymatic activity of alpha- and beta-myosin heavy chain revealed a different temperature dependency. When temperature increased ATPase activity of the alpha-myosin heavy chain isoenzyme increased relatively more than ATPase activity of the beta-myosin heavy chain isoenzyme. Summer animals expressed predominantly the beta-myosin heavy chain (79% of total myosin) while during hibernation the alpha-myosin heavy chain expression increased to 53% of total myosin. Winter-active hamsters kept at 22 degrees C and 12 h day/night rhythm showed the same myosin heavy chain isoenzyme pattern as summer-active animals. Two myosin light chain forms were expressed in the ventricle of all animal groups. The in vivo phosphorylation level of the phosphorylatable myosin light chain decreased from 45% in summer-active hamster to 23% during hibernation.

Details

show
hide
Language(s): eng - English
 Dates: 1991-06-201990-12-181991-06-201992-02-01
 Publication Status: Published in print
 Pages: 7
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Journal of Muscle Research and Cell Motility
  Other : J. Muscle Res. Cell Motil.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: London : Chapman and Hall
Pages: - Volume / Issue: 13 (1) Sequence Number: - Start / End Page: 64 - 70 Identifier: ISSN: 0142-4319
CoNE: https://pure.mpg.de/cone/journals/resource/954925472360