非表示:
キーワード:
alkyl aryl ethers; C-O bond formation; fluorine; Mitsunobu reaction; PhenoFluor
要旨:
An alkyl aryl ether bond formation reaction between phenols and primary and secondary alcohols with PhenoFluor has been developed. The reaction features a broad substrate scope and tolerates many functional groups, and substrates that are challenging for more conventional ether bond forming processes may be coupled. A preliminary mechanistic study indicates reactivity distinct from conventional ether bond formation.
