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  Cytochromes P450 - structural basis for binding and catalysis

von König, K., & Schlichting, I. (2007). Cytochromes P450 - structural basis for binding and catalysis. In A. Sigel, H. Sigel, & R. K. O. Sigel (Eds.), Metal ions in life sciences: the ubiquitous roles of cytochrome P450 proteins; Volume 3 (pp. 235-265). Chichester, UK: Wiley & Sons Ltd. Retrieved from http://onlinelibrary.wiley.com/doi/10.1002/9780470028155.ch8/summary.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002B-34EB-6 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002B-34EC-4
Genre: Book Chapter
Alternative Title : Cytochromes P450 - structural basis for binding and catalysis

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MetIonsLifeSci_3_2007_235.pdf (Any fulltext), 4MB
 
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 Creators:
von König, Konstanze1, Author              
Schlichting, Ilme1, Author              
Affiliations:
1Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society, ou_1497700              

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Free keywords: cytochrome P450 enzymes; P450 structural basis for binding and catalysis; CYP101 architecture; distal acid-alcohol pair; wild-type and mutant CYP107A; CYP158A2 substrate specificity; proton transfer via proton relay system
 Abstract: This chapter contains sections titled: Introduction; Ligand Binding: Substrate Recognition and Access to the Distal Pocket; Architecture of the Active Site of CYP101; The Distal Acid-Alcohol Pair; Experimental Characterization of Reaction Intermediates. Radiolysis as a Tool to Study Redox Reactions; Crystal Structures of Oxy-Ferrous Complexes; Mechanism: Summary, Conclusions, Speculations; Acknowledgments; Abbreviations; References

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Language(s): eng - English
 Dates: 2007-05-112007-03-01
 Publication Status: Published in print
 Pages: 31
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

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Title: Metal ions in life sciences: the ubiquitous roles of cytochrome P450 proteins; Volume 3
Source Genre: Book
 Creator(s):
Sigel, Astrid, Editor
Sigel, Helmut, Editor
Sigel, Roland K. O., Editor
Affiliations:
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Publ. Info: Chichester, UK : Wiley & Sons Ltd.
Pages: XXVI, 652 S. Volume / Issue: 3 Sequence Number: - Start / End Page: 235 - 265 Identifier: ISBN: 978-0-470-01672-5