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  The MSL complex: juggling RNA-protein interaction for dosage compensation and beyond

Keller, C. I., & Akhtar, A. (2015). The MSL complex: juggling RNA-protein interaction for dosage compensation and beyond. Current Opinion in Genetics & Development, 31, 1-11. doi:10.1016/j.gde.2015.03.007.

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Keller et al. 2015.pdf (Publisher version), 699KB
 
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2015
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 Creators:
Keller, Claudia Isabelle1, Author
Akhtar, A.2, Author              
Affiliations:
1Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society, 79108 Freiburg, DE, ou_2243640              
2Department of Chromatin Regulation, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society, ou_2243643              

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 Abstract: The Male Specific Lethal (MSL) complex provides an exquisite example of an epigenetic modulator that is involved in chromosome-wide as well as individual gene regulation in flies and mammals. In this review, we discuss the recent advances in biochemical and structural understanding of the MSL complex modules and how they function in X chromosome regulation in flies. Moreover, we describe possible conserved and dosage compensation-independent functions of the MSL complex with a particular focus on mammalian systems.

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Language(s): eng - English
 Dates: 2015-04-19
 Publication Status: Published online
 Pages: 11
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.gde.2015.03.007
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Title: Current Opinion in Genetics & Development
  Other : Curr. Opin. Genet. Dev.
Source Genre: Journal
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Publ. Info: London : Elsevier Current Trends
Pages: - Volume / Issue: 31 Sequence Number: - Start / End Page: 1 - 11 Identifier: Other: 954925578065
ISSN: 0959-437X
CoNE: https://pure.mpg.de/cone/journals/resource/954925578065