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  Direct Catalytic Synthesis of Unprotected 2‐Amino‐1‐Phenylethanols from Alkenes by Using Iron(II) Phthalocyanine

Legnani, L., & Morandi, B. (2016). Direct Catalytic Synthesis of Unprotected 2‐Amino‐1‐Phenylethanols from Alkenes by Using Iron(II) Phthalocyanine. Angewandte Chemie International Edition, 55, 2248-2251. doi:10.1002/anie.201507630.

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 Creators:
Legnani, Luca1, Author
Morandi, Bill1, Author           
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1Research Group Morandi, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_2040309              

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 Abstract: Aryl-substituted amino alcohols are privileged scaffolds in medicinal chemistry and natural products . Herein, we report that an exceptionally simple and inexpensive Fe II complex efficiently catalyze sthe direct transformation of simple alkenes into unprotected amino alcohols in good yield and perfect regioselectivity .This new catalytic method was applied in the expedient synthesis of bioactive molecules and could be extended to aminoetherification.

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 Dates: 2016-01-14
 Publication Status: Published in print
 Pages: 4
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1002/anie.201507630
 Degree: -

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Title: Angewandte Chemie International Edition
  Other : Angew. Chem., Int. Ed.
  Other : Angew. Chem. Int. Ed.
  Other : Angewandte Chemie, International Edition
Source Genre: Journal
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Publ. Info: Weinheim : Wiley-VCH
Pages: 4 Volume / Issue: 55 Sequence Number: - Start / End Page: 2248 - 2251 Identifier: ISSN: 1433-7851
CoNE: https://pure.mpg.de/cone/journals/resource/1433-7851