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  Clinical trial of modulatory effects of oxytocin treatment on higher-order social cognition in autism spectrum disorder: A randomized, placebo-controlled, double-blind and crossover trial

Preckel, K., Kanske, P., Singer, T., Paulus, F. M., & Krach, S. (2016). Clinical trial of modulatory effects of oxytocin treatment on higher-order social cognition in autism spectrum disorder: A randomized, placebo-controlled, double-blind and crossover trial. BMC Psychiatry, 16: 329. doi:10.1186/s12888-016-1036-x.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002B-4FE8-2 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-1EE0-F
Genre: Journal Article

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Preckel_Kanske_2016.pdf (Publisher version), 699KB
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 Creators:
Preckel, Katrin1, Author              
Kanske, Philipp1, Author              
Singer, Tania1, Author              
Paulus, Frieder M.2, Author
Krach, Sören2, Author
Affiliations:
1Department Social Neuroscience, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634552              
2University Hospital of Schleswig-Holstein, Campus Lübeck, Germany, ou_persistent22              

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Free keywords: Autism spectrum disorder; Oxytocin; Emotional reactivity; Social motivation; Social reward; Empathy; Theory of mind; fMRI; Oxytocin receptor gene
 Abstract: Autism spectrum disorders are neurodevelopmental conditions with severe impairments in social communication and interaction. Pioneering research suggests that oxytocin can improve motivation, cognition and attention to social cues in patients with autism spectrum disorder. The aim of this clinical trial is to characterize basic mechanisms of action of acute oxytocin treatment on neural levels and to relate these to changes in different levels of socio-affective and -cognitive functioning.

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Language(s): eng - English
 Dates: 2016-09-022016-09-092016-09-21
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1186/s12888-016-1036-x
PMID: 27655235
PMC: PMC5031348
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Title: BMC Psychiatry
Source Genre: Journal
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Publ. Info: BioMed Central
Pages: - Volume / Issue: 16 Sequence Number: 329 Start / End Page: - Identifier: ISSN: 1471-244X
CoNE: https://pure.mpg.de/cone/journals/resource/111000136906052