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  NMR spectroscopy in andrology: research uses and possible clinical applications

Rohr, G., Eggert-Kruse, W., & Kalbitzer, H. (1995). NMR spectroscopy in andrology: research uses and possible clinical applications. International journal of andrology, 18(Suppl. 2), 12-19. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/8719853.

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IntJAndrol_18_1995_S12.pdf (Any fulltext), 5MB
 
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 Creators:
Rohr, G., Author
Eggert-Kruse, W., Author
Kalbitzer, HR1, Author              
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1Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497712              

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Free keywords: NMR spectroscopy, semen, seminal plasma, spermatozoa, testis
 Abstract: Research uses and possible clinical applications of NMR spectroscopy are considered. By monitoring extracts of testes using 31P-NMR spectroscopy, detailed analysis of high-energy phosphates, or pathways such as phospholipid biosynthesis or glycolysis, is possible. By using in-vivo 31P NMR spectroscopy of testes in animal experiments it has proved possible to discriminate non-invasively between experimentally impaired and control testes. It has been demonstrated in several human studies that discrimination between normal testes and those with impaired spermatogenesis and obstruction is possible by non-invasive NMR spectroscopy. In studies of semen, seminal plasma or spermatozoa, NMR spectroscopy is of high experimental value for analysis of sample composition, the kinetics of metabolites or the structure of single components, but clinical applications have not yet been clearly defined.

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Language(s): eng - English
 Dates: 1995-12-01
 Publication Status: Published in print
 Pages: 8
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

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Title: International journal of andrology
Source Genre: Journal
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Publ. Info: Copenhagen : Scriptor
Pages: - Volume / Issue: 18 (Suppl. 2) Sequence Number: - Start / End Page: 12 - 19 Identifier: ISSN: 0105-6263