English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Dissecting the functional anatomy of auditory word repetition

Hope, T. M. H., Prejawa, S., Jones, O. P., Oberhuber, M., Seghier, M. L., Green, D. W., et al. (2014). Dissecting the functional anatomy of auditory word repetition. Frontiers in Human Neuroscience, 8: 246. doi:10.3389/fnhum.2014.00246.

Item is

Files

show Files
hide Files
:
Hope_2014.pdf (Publisher version), 2MB
Name:
Hope_2014.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Description:
-

Creators

show
hide
 Creators:
Hope, Thomas M. H.1, Author
Prejawa, Suse1, Author              
Jones, Oiwi Parker1, 2, Author
Oberhuber, Marion1, Author
Seghier, Mohamed L.1, Author
Green, David W.3, Author
Price, Cathy J.1, Author
Affiliations:
1Wellcome Trust Centre for Neuroimaging, University College London, United Kingdom, ou_persistent22              
2Wolfson College, University of Oxford, United Kingdom, ou_persistent22              
3Department of Cognitive, Perceptual and Brain Sciences, Institute of Behavioural Neuroscience, University College London, United Kingdom, ou_persistent22              

Content

show
hide
Free keywords: fMRI; Language; Auditory word repetition
 Abstract: This fMRI study used a single, multi-factorial, within-subjects design to dissociate multiple linguistic and non-linguistic processing areas that are all involved in repeating back heard words. The study compared: (1) auditory to visual inputs; (2) phonological to non-phonological inputs; (3) semantic to non-semantic inputs; and (4) speech production to finger-press responses. The stimuli included words (semantic and phonological inputs), pseudowords (phonological input), pictures and sounds of animals or objects (semantic input), and colored patterns and hums (non-semantic and non-phonological). The speech production tasks involved auditory repetition, reading, and naming while the finger press tasks involved one-back matching. The results from the main effects and interactions were compared to predictions from a previously reported functional anatomical model of language based on a meta-analysis of many different neuroimaging experiments. Although many findings from the current experiment replicated many of those predicted, our within-subject design also revealed novel results by providing sufficient anatomical precision to dissect several different regions within the anterior insula, pars orbitalis, anterior cingulate, SMA, and cerebellum. For example, we found one part of the pars orbitalis was involved in phonological processing and another in semantic processing. We also dissociated four different types of phonological effects in the left superior temporal sulcus (STS), left putamen, left ventral premotor cortex, and left pars orbitalis. Our findings challenge some of the commonly-held opinions on the functional anatomy of language, and resolve some previously conflicting findings about specific brain regions—and our experimental design reveals details of the word repetition process that are not well captured by current models.

Details

show
hide
Language(s): eng - English
 Dates: 2013-08-252014-04-032014-05-06
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.3389/fnhum.2014.00246
PMID: 24834043
PMC: PMC4018561
Other: eCollection 2014
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Frontiers in Human Neuroscience
  Abbreviation : Front Hum Neurosci
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Lausanne, Switzerland : Frontiers Research Foundation
Pages: - Volume / Issue: 8 Sequence Number: 246 Start / End Page: - Identifier: ISSN: 1662-5161
CoNE: https://pure.mpg.de/cone/journals/resource/1662-5161