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  Thermal stress depletes energy reserves in Drosophila.

Klepsatel, P., Gáliková, M., Xu, Y., & Kühnlein, R. (2016). Thermal stress depletes energy reserves in Drosophila. Scientific Reports, 6: 33667. doi:10.1038/srep33667.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002B-6262-B Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002B-6266-3
Genre: Journal Article

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Klepsatel, P.1, Author              
Gáliková, M.1, Author              
Xu, Y.1, Author              
Kühnlein, R.1, Author              
Affiliations:
1Research Group of Molecular Physiology, MPI for Biophysical Chemistry, Max Planck Society, ou_578592              

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 Abstract: Understanding how environmental temperature affects metabolic and physiological functions is of crucial importance to assess the impacts of climate change on organisms. Here, we used different laboratory strains and a wild-caught population of the fruit fly Drosophila melanogaster to examine the effect of temperature on the body energy reserves of an ectothermic organism. We found that permanent ambient temperature elevation or transient thermal stress causes significant depletion of body fat stores. Surprisingly, transient thermal stress induces a lasting “memory effect” on body fat storage, which also reduces survivorship of the flies upon food deprivation later after stress exposure. Functional analyses revealed that an intact heat-shock response is essential to protect flies from temperature-dependent body fat decline. Moreover, we found that the temperature-dependent body fat reduction is caused at least in part by apoptosis of fat body cells, which might irreversibly compromise the fat storage capacity of the flies. Altogether, our results provide evidence that thermal stress has a significant negative impact on organismal energy reserves, which in turn might affect individual fitness.

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Language(s): eng - English
 Dates: 2016-09-19
 Publication Status: Published online
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 Rev. Method: Peer
 Identifiers: DOI: 10.1038/srep33667
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Title: Scientific Reports
Source Genre: Journal
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Pages: 12 Volume / Issue: 6 Sequence Number: 33667 Start / End Page: - Identifier: -