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  X chromosomal regulation in flies: when less is more

Hallacli, E., & Akhtar, A. (2009). X chromosomal regulation in flies: when less is more. Chromosome Research, 603-619.

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 Creators:
Hallacli, Erinc1, Author              
Akhtar, Asifa1, Author              
Affiliations:
1Department of Chromatin Regulation, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society, ou_2243643              

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Free keywords: X chromosome; MSL; Drosophila; transcription; chromatin; roXRNA; acetylation
 Abstract: In Drosophila, dosage compensation of the single male X chromosome involves upregulation of expression of X linked genes. Dosage compensation complex or the male specific lethal (MSL) complex is intimately involved in this regulation. The MSL complex members decorate the male X chromosome by binding on hundreds of sites along the X chromosome. Recent genome wide analysis has brought new light into X chromosomal regulation. It is becoming increasingly clear that although the X chromosome achieves male specific regulation via the MSL complex members, a number of general factors also impinge on this regulation. Future studies integrating these aspects promise to shed more light into this epigenetic phenomenon.

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Language(s): eng - English
 Dates: 2009
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 456280
 Degree: -

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Title: Chromosome Research
  Alternative Title : Chrom. Research
Source Genre: Journal
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Publ. Info: -
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 603 - 619 Identifier: -