English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Ventromedial prefrontal cortex supports affective future simulation by integrating distributed knowledge

Benoit, R. G., Szpunar, K. K., & Schacter, D. L. (2014). Ventromedial prefrontal cortex supports affective future simulation by integrating distributed knowledge. Proceedings of the National Academy of Sciences of the United States of America, 111(46), 16550-16555. doi:10.1073/pnas.1419274111.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002B-7C84-A Version Permalink: http://hdl.handle.net/21.11116/0000-0003-7EDF-6
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Benoit, Roland G.1, 2, Author              
Szpunar, Karl K.1, 2, Author
Schacter, Daniel L.1, 2, Author
Affiliations:
1Department of Psychology, Harvard University, Cambridge, MA, USA, ou_persistent22              
2Center for Brain Science, Harvard University, Cambridge, MA, USA, ou_persistent22              

Content

show
hide
Free keywords: Episodic future thinking; Episodic memory; Functional MRI; Ventromedial prefrontal cortex; Subjective value
 Abstract: Although the future often seems intangible, we can make it more concrete by imagining prospective events. Here, using functional MRI, we demonstrate a mechanism by which the ventromedial prefrontal cortex supports such episodic simulations, and thereby contributes to affective foresight: This region supports processes that (i) integrate knowledge related to the elements that constitute an episode and (ii) represent the episode’s emergent affective quality. The ventromedial prefrontal cortex achieves such integration via interactions with distributed cortical regions that process the individual elements. Its activation then signals the affective quality of the ensuing episode, which goes beyond the combined affective quality of its constituting elements. The integrative process further augments long-term retention of the episode, making it available at later time points. This mechanism thus renders the future tangible, providing a basis for farsighted behavior.

Details

show
hide
Language(s): eng - English
 Dates: 2014-08-222014-11-032014-11-18
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1073/pnas.1419274111
PMID: 25368170
PMC: PMC4246308
Other: Epub 2014
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Proceedings of the National Academy of Sciences of the United States of America
  Abbreviation : PNAS
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Washington, D.C. : National Academy of Sciences
Pages: - Volume / Issue: 111 (46) Sequence Number: - Start / End Page: 16550 - 16555 Identifier: ISSN: 0027-8424
CoNE: https://pure.mpg.de/cone/journals/resource/954925427230