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Abstract:
Antibodies generated against synthetic peptides that correspond to highly conserved sequence motifs in the annexins reacted with a variety of annexins from different species. These include Xenopus laevis and Drosophila melanogaster, which contain cross-reacting polypeptides of apparent Mr, 34000 and 30000. As expected for typical annexins, the two Drosophila proteins interact in a Ca2+-dependent manner with phosphatidylserine liposomes.