English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Continuous flow processes for photoconjugation of high-molecular chemical entities
Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002B-BE8B-7 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002B-BE8C-5
Genre: Patent

Files

show Files
hide Files
:
2364241.pdf (Publisher version), 3MB
Name:
2364241.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Seeberger, Peter H.1, Author              
Laurino, P.2, Author              
Kikkeri, R.2, Author              
O'Brien, Alexander G.2, Author              
Klein, James C.2, Author              
Götze, Sebastian3, Author              
Affiliations:
1Peter H. Seeberger, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_2040285              
2Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863286              
3Daniel Varón Silva, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863302              

Content

show
hide
Free keywords: -
 Abstract: The invention relates to a continuous flow process for the photoconjugation of chemical entities selected from the group comprising carbohydrates, including mono-, oligo- and polysaccharides, amino acids, peptides and proteins, unbranched and branched oligomers and polymers, including dendrimers, which process comprises at least the following steps: a) providing a mixture of the reactants dissolved in an aqueous or organic solvent; b) passing said mixture through a continuous flow reactor and concomitantly irradiating the mixture with light in order to initiate and perform the photoreaction. In preferred embodiments, the photoconjugation is a thiol-ene conjugation or a [2+2] cycloaddition. A further aspect of the invention relates to the conjugates obtainable by this continuous flow process, in particular dendronized polymers such as carbohydrate-dendronized polymers.

Details

show
hide
Language(s):
 Dates: 2011-11-232012-05-31
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: Patent Publication Nr.: WO2013139803 A1
Patent Application Nr.: PCT/EP2011/005898
 Degree: -

Event

show

Legal Case

show

Project information

show

Source

show