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  Synthesis of binary nanopatterns on hydrogels for initiating cellular responses

Guasch, J., Diemer, J., Riahinezhad, H., Neubauer, S., Kessler, H., & Spatz, J. P. (2016). Synthesis of binary nanopatterns on hydrogels for initiating cellular responses. Chemistry of Materials, 28(6), 1806-1815. doi:10.1021/acs.chemmater.5b04910.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002A-1BEF-C Version Permalink: https://hdl.handle.net/11858/00-001M-0000-002E-7D77-B
Genre: Journal Article

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http://pubs.acs.org/doi/pdf/10.1021/acs.chemmater.5b04910 (Any fulltext)
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 Creators:
Guasch, Judit1, 2, Author           
Diemer, Jennifer1, 2, Author           
Riahinezhad, Hossein, Author
Neubauer, Stefanie, Author
Kessler, Horst, Author
Spatz, Joachim P.1, 2, Author           
Affiliations:
1Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_2364731              
2Biophysical Chemistry, Institute of Physical Chemistry, University of Heidelberg, 69120 Heidelberg, Germany, ou_persistent22              

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 Abstract: We describe the synthesis of binary nanostructures consisting of PEG hydrogels decorated with arrays of AuNPs and TiO2NPs, and their orthogonal functionalization with various peptides. These ligands are able to promote or elude cell adhesion through integrins, a family of transmembrane receptors that connect cells with the extracellular matrix (ECM) or other cells. The different cell adhesion behaviors observed depending on the peptides used, proved the functionality of such binary nanopatterns, which we expect to find applications not only in tissue engineering but also in smart cell culture systems and biosensors.

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Language(s): eng - English
 Dates: 2016-02-232015-12-212016-01-01
 Publication Status: Issued
 Pages: 10
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 Rev. Type: Peer
 Identifiers: DOI: 10.1021/acs.chemmater.5b04910
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Title: Chemistry of Materials
  Abbreviation : Chem. Mater.
Source Genre: Journal
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Publ. Info: Washington, D.C. : American Chemical Society
Pages: - Volume / Issue: 28 (6) Sequence Number: - Start / End Page: 1806 - 1815 Identifier: ISSN: 0897-4756
CoNE: https://pure.mpg.de/cone/journals/resource/954925561571