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  Biomimetic models of the actin cytoskeleton

Mohrdieck, C., Dalmas, F., Arzt, E., Tharmann, R., Claessens, M. M. A. E., Bausch, A. R., et al. (2007). Biomimetic models of the actin cytoskeleton. Small, 3(6), 1015-1022. doi:10.1002/smll.200600565.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-4373-9 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002E-7C64-E
Genre: Journal Article

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Small_3_2007_1015.pdf (Any fulltext), 465KB
 
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 Creators:
Mohrdieck, Camilla, Author
Dalmas, Florent, Author
Arzt, Eduard, Author
Tharmann, Rainer, Author
Claessens, Mireille M. A. E., Author
Bausch, Andreas R., Author
Roth, Alexander, Author
Sackmann, Erich, Author
Schmitz, Christian H. J., Author
Curtis, Jennifer E.1, Author              
Roos, Wouter1, Author              
Schulz, Simon1, Author              
Uhrig, Kai1, Author              
Spatz, Joachim P.1, 2, Author              
Affiliations:
1Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_2364731              
2Biophysical Chemistry, Institute of Physical Chemistry, University of Heidelberg, 69120 Heidelberg, Germany, ou_persistent22              

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Free keywords: · cells · mechanical properties · microfluidics · self-assembly · simulations
 Abstract: The cytoskeleton is a complex polymer network that plays an essential role in the functionality of eukaryotic cells. It endows cells with mechanical stability, adaptability, and motility. To identify and understand the mechanisms underlying this large variety of capabilities and to possibly transfer them to engineered networks makes it necessary to have in vitro and in silico model systems of the cytoskeleton. These models must be realistic representatives of the cellular network and at the same time be controllable and reproducible. Here, an approach to design complementary experimental and numerical model systems of the actin cytoskeleton is presented and some of their properties discussed.

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Language(s): eng - English
 Dates: 2007-04-042007-01-112007-05-082007-07-04
 Publication Status: Published in print
 Pages: 8
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 318067
DOI: 10.1002/smll.200600565
 Degree: -

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Title: Small
  Other : Small
Source Genre: Journal
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Publ. Info: Weinheim, Germany : Wiley
Pages: - Volume / Issue: 3 (6) Sequence Number: - Start / End Page: 1015 - 1022 Identifier: ISSN: 1613-6810
CoNE: https://pure.mpg.de/cone/journals/resource/1000000000017440_1