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  Technique of surface modification of a cell-adhesion resistant hydrogel by a cell-adhesion-available inorganic microarray

Sun, J., Graeter, S. V., Yu, L., Duan, S., Spatz, J. P., & Ding, J. (2008). Technique of surface modification of a cell-adhesion resistant hydrogel by a cell-adhesion-available inorganic microarray. Biomacromolecules, 9(10), 2569-2572. doi:10.1021/bm800477s.

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 Creators:
Sun, Jianguo, Author
Graeter, Stefan V.1, Author           
Yu, Lin, Author
Duan, Shifeng, Author
Spatz, Joachim P.1, 2, Author           
Ding, Jiandong, Author
Affiliations:
1Cellular Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_2364731              
2Biophysical Chemistry, Institute of Physical Chemistry, University of Heidelberg, 69120 Heidelberg, Germany, ou_persistent22              

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 Abstract: A microtransfer technique for micropattern fabrication using a dithiol macromolecular linker is suggested by transferring a conventionally photolithography-prepared gold microarray on a hard inorganic substrate to a polymeric substrate. The linker was synthesized by end-capping a poly(ethylene glycol) (PEG) chain by the thiol groups. The efficiency of this technique is demonstrated by the transfer of gold microdots from glass to a cell-adhesion-resistant PEG hydrogel, which was formed by polymerizing PEG diacrylate macromers. The stability and biocompatibility of the resulting polymeric-inorganic hybrid material and cell-adhesion contrast of the patterned surface is confirmed by preliminary cell experiments.

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Language(s): eng - English
 Dates: 2008-06-252008-04-302008-07-232008-07-232008-10-01
 Publication Status: Issued
 Pages: 4
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 Rev. Type: Peer
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Title: Biomacromolecules
  Other : Biomacromolecules
Source Genre: Journal
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Publ. Info: Washington, DC : American Chemical Society
Pages: - Volume / Issue: 9 (10) Sequence Number: - Start / End Page: 2569 - 2572 Identifier: ISSN: 1525-7797
CoNE: https://pure.mpg.de/cone/journals/resource/969870273004