English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  The DnaK/ClpB chaperone system from Thermus thermophilus

Schlee, S., & Reinstein, J. (2002). The DnaK/ClpB chaperone system from Thermus thermophilus. Cellular and Molecular Life Sciences, 59(10), 1598-1606. doi:10.1007/PL00012486.

Item is

Basic

show hide
Genre: Journal Article
Alternative Title : The DnaK/ClpB chaperone system from Thermus thermophilus

Files

show Files
hide Files
:
CellMolLifeSci_59_2002_1598.pdf (Any fulltext), 167KB
 
File Permalink:
-
Name:
CellMolLifeSci_59_2002_1598.pdf
Description:
-
OA-Status:
Visibility:
Restricted (Max Planck Institute for Medical Research, MHMF; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Description:
-
OA-Status:
Locator:
https://dx.doi.org/10.1007/PL00012486 (Any fulltext)
Description:
-
OA-Status:

Creators

show
hide
 Creators:
Schlee, Sandra1, Author           
Reinstein, Jochen1, Author           
Affiliations:
1Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society, ou_1497700              

Content

show
hide
Free keywords: Protein folding; chaperone; DnaK; DnaJ; GrpE; ClpB; heat-shock; thermophile
 Abstract: Proteins of thermophilic organisms are adapted to remain well structured and functional at elevated temperatures. Nevertheless like their 'cousins' that reside at medium temperatures, they require the assistance of molecular chaperones to fold properly and prevent aggregation. This review compares structural and functional properties of the DnaK/ClpB systems of Thermus thermophilus and, mainly, Escherichia coli (DnaK(Tth) and DnaK(Eco)). Many elemental properties of these systems remain conserved. However, in addition to a general increase of the thermal stability of its components, the DnaK(Tth) system shows profound differences in its regulation, and genetic as well as oligomeric organization. Whether these differences are unique or represent general strategies of adaptation to life at elevated temperatures remains to be clarified.

Details

show
hide
Language(s): eng - English
 Dates: 2002-10-01
 Publication Status: Published in print
 Pages: 9
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 665716
DOI: 10.1007/PL00012486
URI: http://www.ncbi.nlm.nih.gov/pubmed/12475169
Other: 6230
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Cellular and Molecular Life Sciences
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Basel : Birkha.user Verlag
Pages: - Volume / Issue: 59 (10) Sequence Number: - Start / End Page: 1598 - 1606 Identifier: ISSN: 1420-682X
CoNE: https://pure.mpg.de/cone/journals/resource/954926942730