English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Number and laminar distribution of neurons in a thalamocortical projection column of rat vibrissal cortex

Meyer, H.-S., Wimmer, V. C., Oberlaender, M., de Kock, C., Sakmann, B., & Helmstaedter, M. (2010). Number and laminar distribution of neurons in a thalamocortical projection column of rat vibrissal cortex. Cerebral Cortex, 20(10), 2277-2286. doi:10.1093/cercor/bhq067.

Item is

Basic

show hide
Genre: Journal Article
Alternative Title : Number and laminar distribution of neurons in a thalamocortical projection column of rat vibrissal cortex

Files

show Files
hide Files
:
CerebCortex_20_ 2010_2277.pdf (Any fulltext), 2MB
 
File Permalink:
-
Name:
CerebCortex_20_ 2010_2277.pdf
Description:
-
OA-Status:
Visibility:
Restricted (Max Planck Institute for Medical Research, MHMF; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Description:
-
OA-Status:
Locator:
https://doi.org/10.1093/cercor/bhq067 (Any fulltext)
Description:
-
OA-Status:

Creators

show
hide
 Creators:
Meyer, Hanno-Sebastian1, Author           
Wimmer, Verena C.1, Author           
Oberlaender, Marcel1, Author           
de Kock, Christiaan1, Author           
Sakmann, Bert1, Author           
Helmstaedter, Moritz1, Author           
Affiliations:
1Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497701              

Content

show
hide
Free keywords: cortex layer; neuron density; POm; somatosensory barrel cortex; VPM
 Abstract: This is the second article in a series of three studies that investigate the anatomical determinants of thalamocortical (TC) input to excitatory neurons in a cortical column of rat primary somatosensory cortex (S1). Here, we report the number and distribution of NeuN-positive neurons within the C2, D2, and D3 TC projection columns in P27 rat somatosensory barrel cortex based on an exhaustive identification of 89,834 somata in a 1.15 mm(3) volume of cortex. A single column contained 19,109 ± 444 neurons (17,560 ± 399 when normalized to a standard-size projection column). Neuron density differences along the vertical column axis delineated "cytoarchitectonic" layers. The resulting neuron numbers per layer in the average column were 63 ± 10 (L1), 2039 ± 524 (L2), 3735 ± 905 (L3), 4447 ± 439 (L4), 1737 ± 251 (L5A), 2235 ± 99 (L5B), 3786 ± 168 (L6A), and 1066 ± 170 (L6B). These data were then used to derive the layer-specific action potential (AP) output of a projection column. The estimates confirmed previous reports suggesting that the ensembles of spiny L4 and thick-tufted pyramidal neurons emit the major fraction of APs of a column. The number of APs evoked in a column by a sensory stimulus (principal whisker deflection) was estimated as 4441 within 100 ms post-stimulus.

Details

show
hide
Language(s): eng - English
 Dates: 2010-06-092010-10-01
 Publication Status: Published in print
 Pages: 10
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 664505
DOI: 10.1093/cercor/bhq067
URI: http://www.ncbi.nlm.nih.gov/pubmed/20534784
Other: 7665
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Cerebral Cortex
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: New York, NY : Oxford University Press
Pages: - Volume / Issue: 20 (10) Sequence Number: - Start / End Page: 2277 - 2286 Identifier: ISSN: 1047-3211
CoNE: https://pure.mpg.de/cone/journals/resource/954925592440