English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Quantal charge redistributions accompanying the structural transitions of sodium channels.

Conti, F., & Stühmer, W. (1989). Quantal charge redistributions accompanying the structural transitions of sodium channels. European Biophysics Journal, 17(2), 53-59. doi:10.1007/BF00257102.

Item is

Files

show Files
hide Files
:
2403154.pdf (Publisher version), 718KB
Name:
2403154.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Conti, F., Author
Stühmer, W.1, Author              
Affiliations:
1Department of Membrane Biophysics, MPI for biophysical chemistry, Max Planck Society, ou_578579              

Content

show
hide
Free keywords: -
 Abstract: Asymmetric displacement currents, Ig, associated with the gating of nerve sodium channels have been recorded in cell-attached macropatches of Xenopus laevis oocytes injected with exogenous mRNA coding for rat-brain-II sodium channels. The Ig properties were found to be similar to those of gating currents previously observed in native nerve preparations. Ig fluctuations were measured in order to ascertain the discreteness of the conformational changes which precede the channel opening. The autocorrelation of the fluctuations is consistent with a shot-like character of the elementary Ig contributions. The variance of the fluctuations indicates that most of the gating-charge movement that accompanies the activation of a single sodium channel occurs in 2 to 3 brief packets, each carrying an equivalent of about 2.3 electron charges.

Details

show
hide
Language(s): eng - English
 Dates: 1989-06
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1007/BF00257102
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: European Biophysics Journal
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 17 (2) Sequence Number: - Start / End Page: 53 - 59 Identifier: -