Asymmetric Catalysis of the Carbonyl-Amine Condensation: Kinetic Resolution of 
Primary Amines

Das, Sayantani; Majumdar, Nilanjana; De, Chandra Kanta; Kundu, Dipti Sankar; Döhring, Arno; Garczynski, Anika; List, Benjamin

doi:10.1021/jacs.6b12176

Item

ITEM ACTIONSEXPORT

Add to Basket

Please note that a newer version of this item is available:
https://pure.mpg.de/pubman/item/item_2406802_5

DetailsSummary

Asymmetric Catalysis of the Carbonyl-Amine Condensation: Kinetic Resolution of Primary Amines

Das, S., Majumdar, N., De, C. K., Kundu, D. S., Döhring, A., Garczynski, A., et al. (2017). Asymmetric Catalysis of the Carbonyl-Amine Condensation: Kinetic Resolution of Primary Amines. Journal of the American Chemical Society, 139(4), 1357-1359. doi:10.1021/jacs.6b12176.

Item is Released

show all hide all

Basic

show hide

Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002C-A18F-6 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-002C-A190-D

Genre: Journal Article

Files

show Files

Locators

show

Creators

show

hide

Creators:
Das, Sayantani¹, Author
Majumdar, Nilanjana¹, Author
De, Chandra Kanta¹, Author
Kundu, Dipti Sankar², Author
Döhring, Arno¹, Author
Garczynski, Anika¹, Author
List, Benjamin¹, Author

Affiliations:
1Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445585
2RWTH Aachen University, ou_persistent22

Content

show

hide

Free keywords: -

Abstract: A Brønsted acid catalyzed kinetic resolution of primary amines is described that is based on the condensation between an amine and a carbonyl compound. 1,3-Diketones react with racemic α-branched amines to furnish the corresponding enantioenriched enaminone and recovered starting material. Good to excellent enantioselectivity was observed with both aromatic and aliphatic primary amines. This process represents the first small-molecule catalyzed kinetic resolution of aliphatic amines.

Details

show

hide

Language(s): eng - English

Dates: Submitted: 2016-11-25Published Online: 2017-01-17Date issued: 2017-02-01

Publication Status: Issued

Pages: 3

Publishing info: -

Table of Contents: -

Rev. Type: Peer

Identifiers: DOI: 10.1021/jacs.6b12176

Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show

hide

Title: Journal of the American Chemical Society

Other : J. Am. Chem. Soc.

Abbreviation : JACS

Source Genre: Journal

Creator(s):

Affiliations:

Publ. Info: Washington, DC : American Chemical Society

Pages: - Volume / Issue: 139 (4) Sequence Number: - Start / End Page: 1357 - 1359 Identifier: ISSN: 0002-7863
CoNE: https://pure.mpg.de/cone/journals/resource/954925376870