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  Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors

Zhang, T., Kwiatkowski, N., Olson, C. M., Dixon-Clarke, S. E., Abraham, B. J., Greifenberg, A. K., et al. (2016). Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Nature Chemical Biology, 12, 876-884. doi:doi:10.1038/nchembio.2166.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002C-F6D5-C Version Permalink: https://hdl.handle.net/21.11116/0000-0001-74DA-7
Genre: Journal Article

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http://www.nature.com/nchembio/journal/v12/n10/full/nchembio.2166.html (Publisher version)
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 Creators:
Zhang, T., Author
Kwiatkowski, N., Author
Olson, C. M., Author
Dixon-Clarke, S. E., Author
Abraham, B. J., Author
Greifenberg , Ann K.1, Author
Ficarro, S. B., Author
Elkins, J. M., Author
Liang, Y., Author
Hannett, N. M., Author
Manz, T., Author
Hao, M., Author
Bartkowiak, B., Author
Greenleaf, A. L., Author
Marrto, J. A., Author
Geyer, Matthias1, Author
Bullock, A. N., Author
Young , R. A., Author
Gray, N. S., Author
Affiliations:
1Center of Advanced European Studies and Research (caesar), Max Planck Society, Ludwig-Erhard-Allee 2, 53175 Bonn, DE, ou_2173675              

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Free keywords: Cancer therapy, Kinases, Small molecules, Transcription
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 Dates: 2016-08-292016-10
 Publication Status: Issued
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 Rev. Type: Peer
 Identifiers: DOI: doi:10.1038/nchembio.2166
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Title: Nature Chemical Biology
  Other : Nat. Chem. Biol.
Source Genre: Journal
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Publ. Info: New York, NY : Nature Pub. Group
Pages: - Volume / Issue: 12 Sequence Number: - Start / End Page: 876 - 884 Identifier: ISSN: 1552-4450
CoNE: https://pure.mpg.de/cone/journals/resource/1000000000021290_1