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  Simultaneous mapping of water shift and B-1(WASABI)-Application to field-inhomogeneity correction of CEST MRI data.

Schuenke, P., Windschuh, J., Roeloffs, V. B., Ladd, M. E., Bachert, P., & Zaiss, M. (2017). Simultaneous mapping of water shift and B-1(WASABI)-Application to field-inhomogeneity correction of CEST MRI data. Magnetic Resonance in Medicine, 77(2), 571-580. doi:10.1002/mrm.26133.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-0A68-F Version Permalink: http://hdl.handle.net/21.11116/0000-0001-4F23-0
Genre: Journal Article

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Schuenke, P., Author
Windschuh, J., Author
Roeloffs, V. B.1, Author              
Ladd, M. E., Author
Bachert, P., Author
Zaiss, M., Author
Affiliations:
1Biomedical NMR Research GmbH, MPI for Biophysical Chemistry, Max Planck Society, ou_578634              

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Free keywords: field mapping; B0 mapping; B 1 mapping; WASABI; CEST
 Abstract: Purpose Together with the development of MRI contrasts that are inherently small in their magnitude, increased magnetic field accuracy is also required. Hence, mapping of the static magnetic field (B0) and the excitation field (B1) is not only important to feedback shim algorithms, but also for postprocess contrast-correction procedures. Methods A novel field-inhomogeneity mapping method is presented that allows simultaneous mapping of the water shift and B1 (WASABI) using an off-resonant rectangular preparation pulse. The induced Rabi oscillations lead to a sinc-like spectrum in the frequency-offset dimension and allow for determination of B0 by its symmetry axis and of B1 by its oscillation frequency. Results Stability of the WASABI method with regard to the influences of T1, T2, magnetization transfer, and repetition time was investigated and its convergence interval was verified. B0 and B1 maps obtained simultaneously by means of WASABI in the human brain at 3 T and 7 T can compete well with maps obtained by standard methods. Finally, the method was applied successfully for B0 and B1 correction of chemical exchange saturation transfer MRI (CEST-MRI) data of the human brain. Conclusion The proposed WASABI method yields a novel simultaneous B0 and B1 mapping within 1 min that is robust and easy to implement. Magn Reson Med 77:571–580, 2017. © 2016 International Society for Magnetic Resonance in Medicine

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Language(s): eng - English
 Dates: 2016-02-092017-02
 Publication Status: Published in print
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 Rev. Method: Peer
 Identifiers: DOI: 10.1002/mrm.26133
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Title: Magnetic Resonance in Medicine
Source Genre: Journal
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Pages: - Volume / Issue: 77 (2) Sequence Number: - Start / End Page: 571 - 580 Identifier: -