Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

 
 
DownloadE-Mail
  Molecular simulation and modeling of complex I

Hummer, G., & Wikström, M. (2016). Molecular simulation and modeling of complex I. Biochimica et Biophysica Acta, Bioenergetics, 1857(7), 915-921. doi:10.1016/j.bbabio.2016.01.005.

Item is

Basisdaten

einblenden: ausblenden:
Genre: Zeitschriftenartikel

Externe Referenzen

einblenden:

Urheber

einblenden:
ausblenden:
 Urheber:
Hummer, Gerhard1, Autor           
Wikström, Mårten2, Autor
Affiliations:
1Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Max Planck Society, ou_2068292              
2Institute of Biotechnology, University of Helsinki, FI-00014 Helsinki, Finland, ou_persistent22              

Inhalt

einblenden:
ausblenden:
Schlagwörter: Cell respiration; Proton pump; Membrane transport; Mitochondria; Proton transfer; Electron transfer
 Zusammenfassung: Molecular modeling and molecular dynamics simulations play an important role in the functional characterization of complex I. With its large size and complicated function, linking quinone reduction to proton pumping across a membrane, complex I poses unique modeling challenges. Nonetheless, simulations have already helped in the identification of possible proton transfer pathways. Simulations have also shed light on the coupling between electron and proton transfer, thus pointing the way in the search for the mechanistic principles underlying the proton pump. In addition to reviewing what has already been achieved in complex I modeling, we aim here to identify pressing issues and to provide guidance for future research to harness the power of modeling in the functional characterization of complex I.

Details

einblenden:
ausblenden:
Sprache(n): eng - English
 Datum: 2015-11-302016-01-072016-01-112016-07
 Publikationsstatus: Erschienen
 Seiten: 7
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1016/j.bbabio.2016.01.005
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: Biochimica et Biophysica Acta, Bioenergetics
  Kurztitel : Biochim. Biophys. Acta, Bioenerg.
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: Amsterdam : Elsevier
Seiten: - Band / Heft: 1857 (7) Artikelnummer: - Start- / Endseite: 915 - 921 Identifikator: ISSN: 0005-2728
CoNE: https://pure.mpg.de/cone/journals/resource/954926938702_6