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  The influence of relaxing factor on the pH dependence of the contraction of muscle models

Briggs, F. N., & Portzehl, H. (1957). The influence of relaxing factor on the pH dependence of the contraction of muscle models. Biochimica et Biophysica Acta, Bioenergetics, 24(24), 482-488. doi:10.1016/0006-3002(57)90236-6.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-2178-D Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-21F8-F
Genre: Journal Article

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BBA_24_1957_482.pdf (Any fulltext), 455KB
 
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 Creators:
Briggs, F. N., Author
Portzehl, Hildegard1, Author              
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1Max Planck Institute for Medical Research, Max Planck Society, ou_1125545              

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 Abstract: 1. The true ratio of tensions of glycerol-extracted muscle fibers at pH 6 to pH 7 is 1:2. 2. 2. This ratio is uninfluenced by the presence of creatine phosphorylase and phosphocreatine. 3. 3. When the true ratio is obscured by employing muscle fibers of excessive diameter or fiber bundles or by utilizing ATP concentrations too low to penetrate the muscle fiber, then the PC system by restoring ATP will reveal the true tension ratio. 4. 4. Although relaxing factor is effective at both pH 6 and pH 7 it is effective at pH 6 over a wider range of concentrations of ATP than at pH 7. 5. 5. Thus the “relaxation” produced by the PC system depends either on the presence of relaxing factor or on revealing the true equilibrium tension when this is obscured by inappropriate experimental techniques.

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Language(s): eng - English
 Dates: 1957-01-031957
 Publication Status: Published in print
 Pages: 7
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/0006-3002(57)90236-6
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Title: Biochimica et Biophysica Acta, Bioenergetics
  Abbreviation : Biochim. Biophys. Acta, Bioenerg.
Source Genre: Journal
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Publ. Info: Amsterdam : Elsevier
Pages: - Volume / Issue: 24 (24) Sequence Number: - Start / End Page: 482 - 488 Identifier: ISSN: 0005-2728
CoNE: https://pure.mpg.de/cone/journals/resource/954926938702_6