English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine.

Duprey, P., Chowdhury, K., Dressler, G., Balling, R., Simon, D., Guenet, J. L., et al. (1988). A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine. Genes and Development, 2(12A), 1647-1654. doi:10.1101/gad.2.12a.1647.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-2BF5-3 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-2BF7-0
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Duprey, P., Author
Chowdhury, K.1, Author              
Dressler, G.R.2, Author              
Balling, R.2, Author              
Simon, D., Author
Guenet, J. L., Author
Gruß, P.2, Author              
Affiliations:
1Department of Molecular Cell Biology, MPI for Biophysical Chemistry, Max Planck Society, ou_578585              
2Department of Molecular Cell Biology, MPI for biophysical chemistry, Max Planck Society, ou_578585              

Content

show
hide
Free keywords: -
 Abstract: A mouse gene, Cdx-1, was isolated from an embryonic cDNA library using a Drosophila caudal gene probe. The deduced amino acid sequence of Cdx-1 contains conserved sequence domains along the entire gene, as well as a highly conserved caudal-type homeo box. A structural comparison suggests a common ancestral origin of mouse Cdx-1 and Drosophila caudal. The expression of Cdx-1 during embryogenesis was analyzed by Northern blotting and in situ hybridization. Cdx-1-specific transcripts are localized in the epithelial lining of the intestines beginning at 14 days' gestation. The expression of Cdx-1 in the intestine continues into adulthood, but cannot be detected in any other tissues. The Cdx-1 gene is the first homeo-box-containing gene expressed in cells derived from the embryonic endoderm.

Details

show
hide
Language(s): eng - English
 Dates: 1988-12
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1101/gad.2.12a.1647
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Genes and Development
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 2 (12A) Sequence Number: - Start / End Page: 1647 - 1654 Identifier: -