Nucleotide based covalent inhibitors of KRas can only be efficient in vivo if 
they bind reversibly with GTP-like affinity

Müller, Matthias; Jeganathan, Sadasivam; Heidrich, Angelika; Campos, Jeremy; Goody, Roger S.

doi:10.1038/s41598-017-03973-6

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Nucleotide based covalent inhibitors of KRas can only be efficient in vivo if they bind reversibly with GTP-like affinity

Müller, M., Jeganathan, S., Heidrich, A., Campos, J., & Goody, R. S. (2017). Nucleotide based covalent inhibitors of KRas can only be efficient in vivo if they bind reversibly with GTP-like affinity. Scientific Reports, 7: 3687, pp. 1-11. doi:10.1038/s41598-017-03973-6.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002D-75C8-9 Version Permalink: https://hdl.handle.net/21.11116/0000-0005-1865-F

Genre: Journal Article

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Creators:
Müller, Matthias¹, Author
Jeganathan, Sadasivam¹, Author
Heidrich, Angelika¹, Author
Campos, Jeremy¹, Author
Goody, Roger S.¹, Author

Affiliations:
1Abt. III: Strukturbiochemie, Max Planck Institute of Molecular Physiology, Max Planck Society, ou_2040307

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Language(s): eng - English

Dates: Published Online: 2017-06-17

Publication Status: Published online

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Rev. Type: Peer

Identifiers: DOI: 10.1038/s41598-017-03973-6

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Title: Scientific Reports

Abbreviation : Sci. Rep.

Source Genre: Journal

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Publ. Info: London, UK : Nature Publishing Group

Pages: - Volume / Issue: 7 Sequence Number: 3687 Start / End Page: 1 - 11 Identifier: ISSN: 2045-2322
CoNE: https://pure.mpg.de/cone/journals/resource/2045-2322