English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Angular velocity integration in a fly heading circuit

Turner-Evans, D., Wegener, S., Rouault, H., Franconville, R., Wolff, T., Seelig, J. D., et al. (2017). Angular velocity integration in a fly heading circuit. eLife, 6: e23496. doi:10.7554/eLife.23496.

Item is

Files

show Files
hide Files
:
Tuner_2017_Angular.pdf (Publisher version), 9MB
Name:
Tuner_2017_Angular.pdf
Description:
-
OA-Status:
Not specified
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Locator:
https://elifesciences.org/articles/23496 (Publisher version)
Description:
-
OA-Status:
Not specified

Creators

show
hide
 Creators:
Turner-Evans, D., Author
Wegener, S., Author
Rouault, H., Author
Franconville, R., Author
Wolff, T., Author
Seelig, Johannes Dominik1, Author           
Druckmann, S., Author
Jayaraman, V., Author
Affiliations:
1Max Planck Research Group Neural Circuits, Center of Advanced European Studies and Research (caesar), Max Planck Society, ou_2237639              

Content

show
hide
Free keywords: D. melanogaster; electrophysiology; internal representation; modeling; navigation; neural circuits; neuroscience; two-photon calcium imaging
 Abstract: Many animals maintain an internal representation of their heading as they move through their surroundings. Such a compass representation was recently discovered in a neural population in the Drosophila melanogaster central complex, a brain region implicated in spatial navigation. Here, we use two-photon calcium imaging and electrophysiology in head-fixed walking flies to identify a different neural population that conjunctively encodes heading and angular velocity, and is excited selectively by turns in either the clockwise or counterclockwise direction. We show how these mirror-symmetric turn responses combine with the neurons' connectivity to the compass neurons to create an elegant mechanism for updating the fly's heading representation when the animal turns in darkness. This mechanism, which employs recurrent loops with an angular shift, bears a resemblance to those proposed in theoretical models for rodent head direction cells. Our results provide a striking example of structure matching function for a broadly relevant computation.

Details

show
hide
Language(s): eng - English
 Dates: 2017-05-22
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.7554/eLife.23496
PMID: 28530551
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: eLife
  Abbreviation : Elife
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cambridge : eLife Sciences Publications
Pages: - Volume / Issue: 6 Sequence Number: e23496 Start / End Page: - Identifier: Other: 2050-084X
CoNE: https://pure.mpg.de/cone/journals/resource/2050-084X