English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Olfactory coding from the periphery to higher brain centers in the Drosophila brain

Seki, Y., Dweck, H., Rybak, J., Wicher, D., Sachse, S., & Hansson, B. S. (2017). Olfactory coding from the periphery to higher brain centers in the Drosophila brain. BMC Biology, 15: 56. doi:10.1186/s12915-017-0389-z.

Item is

Files

show Files
hide Files
:
HAN291.pdf (Publisher version), 10MB
Name:
HAN291.pdf
Description:
-
OA-Status:
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-
:
HAN291s1.zip (Supplementary material), 151MB
Name:
HAN291s1.zip
Description:
-
OA-Status:
Visibility:
Public
MIME-Type / Checksum:
application/zip / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Locator:
http://dx.doi.org/10.1186/s12915-017-0389-z (Publisher version)
Description:
OA
OA-Status:

Creators

show
hide
 Creators:
Seki, Yoichi1, Author           
Dweck, Hany1, 2, Author           
Rybak, Jürgen1, Author           
Wicher, Dieter1, Author           
Sachse, Silke3, Author           
Hansson, Bill S.1, Author           
Affiliations:
1Department of Evolutionary Neuroethology, Prof. B. S. Hansson, MPI for Chemical Ecology, Max Planck Society, ou_421894              
2IMPRS on Ecological Interactions, MPI for Chemical Ecology, Max Planck Society, Jena, DE, ou_421900              
3Research Group Dr. S. Sachse, Olfactory Coding, MPI for Chemical Ecology, Max Planck Society, ou_421914              

Content

show
hide
Free keywords: -
 Abstract: Background Odor information is processed through multiple receptor-glomerular channels in the first order olfactory center, the antennal lobe (AL), then reformatted into higher brain centers and eventually perceived by the fly. To reveal the logic of olfaction, it is fundamental to map odor representations from the glomerular channels into higher brain centers. Results We characterize odor response profiles of AL projection neurons (PNs) originating from 31 glomeruli using whole cell patch-clamp recordings in Drosophila melanogaster. We reveal that odor representation from olfactory sensory neurons to PNs is generally conserved, while transformation of odor tuning curves is glomerulus-dependent. Reconstructions of PNs reveal that attractive and aversive odors are represented in different clusters of glomeruli in the AL. These separate representations are preserved into higher brain centers, where attractive and aversive odors are segregated into two regions in the lateral horn and partly separated in the mushroom body calyx. Conclusions Our study reveals spatial representation of odor valence coding from the AL to higher brain centers. These results provide a global picture of the olfactory circuit design underlying innate odor-guided behavior.

Details

show
hide
Language(s):
 Dates: 2017-06-022017-06-30
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: Other: HAN291
DOI: 10.1186/s12915-017-0389-z
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: BMC Biology
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Berlin ; Heidelberg : Springer
Pages: - Volume / Issue: 15 Sequence Number: 56 Start / End Page: - Identifier: ISSN: 1741-7007
CoNE: https://pure.mpg.de/cone/journals/resource/111071069889000