English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Brain’s functional network correlates of conscious somatosensory perception

Grund, M., Forschack, N., Nierhaus, T., & Villringer, A. (2017). Brain’s functional network correlates of conscious somatosensory perception. Talk presented at 21st Annual Meeting of the Association for Scientific Study of Consciousness (ASSC 21). Beijing, China. 2017-06-13 - 2017-06-16.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-9B25-6 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002D-9B26-4
Genre: Talk

Files

show Files

Locators

show
hide
Locator:
http://www.theassc.org/assc_21_preliminary_program (Supplementary material)
Description:
-

Creators

show
hide
 Creators:
Grund, Martin1, Author              
Forschack, Norman1, Author              
Nierhaus, Till1, Author              
Villringer, Arno1, Author              
Affiliations:
1Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              

Content

show
hide
Free keywords: Perceptual awareness, conscious somatosensory perception, fMRI, neural network, graph theory
 Abstract: Does stimulus awareness modulate the brain’s functional network topology? If network topologies have explanatory power beyond BOLD signal contrasts, they will serve as promising candidates for a neural account of awareness as suggested by the global workspace theory (Baars, 1988). We acquired sub-second fMRI data (TR=0.75s) while participants (N=38) had to report the perception of near-threshold electrical pulses applied at their left index finger and their confidence about this yes/no decision. Additionally there were supra-threshold and catch trials. To evaluate BOLD signal differences, we calculated general linear models with AFNI including stimulus condition specific regressors and response onset regressors. Individual whole-brain functional networks were constructed with the generalized psychophysiological interaction (gPPI; McLaren et al., 2012) between 264 brain-wide nodes (Power et al., 2011). The gPPI tests for context-modulated functional connectivity changes beyond local BOLD signal changes and baseline functional connectivity. The graph theoretical analysis of the connectivity matrixes was performed with the Brain Connectivity Toolbox (Rubinov & Sporns, 2010) to test for global changes of integration and segregation metrics. The BOLD contrast for confident misses and hits revealed several brain areas with a positive signal change across a frontal-parietal network. Interestingly confident misses compared to correct rejections (~97% of catch trials) showed different patterns: (a) early sensory and frontal areas (S1, S2, insula, IFG, & MCC) showed a larger signal for confident misses than correct rejections while (b) parietal areas (precuneus, IPL, & cerebellum) showed a lower signal for confident misses than correct rejections. Despite these activation differences the accompanying functional network alterations showed no graph analytical differences between confident hits, misses and correct rejections. The data shows that the BOLD signal correlates with conscious somatosensory perception in early sensory as well as frontal and parietal areas. Different from Godwin et al. (2015) who reported that visual stimulus awareness is accompanied by a decreased brain’s functional network modularity, somatosensory awareness does not alter the functional connectivity of whole-brain networks.

Details

show
hide
Language(s):
 Dates: 2017-06
 Publication Status: Not specified
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: -
 Degree: -

Event

show
hide
Title: 21st Annual Meeting of the Association for Scientific Study of Consciousness (ASSC 21)
Place of Event: Beijing, China
Start-/End Date: 2017-06-13 - 2017-06-16

Legal Case

show

Project information

show

Source

show