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  Using the Neandertal genome to study the evolution of small insertions and deletions in modern humans

Chintalapati, M., Dannemann, M., & Prüfer, K. (2017). Using the Neandertal genome to study the evolution of small insertions and deletions in modern humans. BMC Evolutionary Biology, 17: 179. doi:10.1186/s12862-017-1018-8.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002D-B9F7-D Version Permalink: https://hdl.handle.net/21.11116/0000-000B-9886-2
Genre: Journal Article

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Chintalapati_Using_BMCEvoBio_2017.pdf (Publisher version), 564KB
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This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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 Creators:
Chintalapati, Manjusha1, 2, Author                 
Dannemann, Michael3, Author                 
Prüfer, Kay2, Author                 
Affiliations:
1The Leipzig School of Human Origins (IMPRS), Max Planck Institute for Evolutionary Anthropology, Max Planck Society, ou_1497688              
2Genomes, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society, ou_2074331              
3The Minerva Research Group for Bioinformatics, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society, ou_2074303              

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 Abstract: Small insertions and deletions occur in humans at a lower rate compared to nucleotide changes, but evolve under more constraint than nucleotide changes. While the evolution of insertions and deletions have been investigated using ape outgroups, the now available genome of a Neandertal can shed light on the evolution of indels in more recent times.

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Language(s): eng - English
 Dates: 2017-08-04
 Publication Status: Published online
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 Rev. Type: Peer
 Identifiers: DOI: 10.1186/s12862-017-1018-8
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Title: BMC Evolutionary Biology
  Alternative Title : BMC Evolutionary Biology
Source Genre: Journal
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Pages: - Volume / Issue: 17 Sequence Number: 179 Start / End Page: - Identifier: ISSN: 1471-2148