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  Sensing the mechano-chemical properties of the extracellular matrix.

Ringer, P., Colo, G., Fässler, R., & Grashoff, C. (2017). Sensing the mechano-chemical properties of the extracellular matrix. Matrix Biology, 64, 6-16. doi:10.1016/j.matbio.2017.03.004.

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1-s2.0-S0945053X17300185-main.pdf (Publisher version), 2MB
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1-s2.0-S0945053X17300185-main.pdf
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© 2017 The Authors. Under a Creative Commons license
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 Creators:
Ringer, Pia1, Author              
Colo, Georgina2, Author              
Fässler, Reinhard2, Author              
Grashoff, Carsten1, Author              
Affiliations:
1Grashoff, Carsten / Molecular Mechanotransduction, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565150              
2Fässler, Reinhard / Molecular Medicine, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565147              

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Free keywords: Extracellular matrix; Focal adhesion; Integrin; Mechanotransduction
 Abstract: The ability of cells to adhere and sense their mechano-chemical environment is key to many developmental, postnatal homeostatic and pathological processes; however, the underlying molecular mechanisms are still poorly understood. Here, we summarize recent progress that indicates how cell adhesion, mechanotransduction and chemical signaling are coordinated in cells, and we discuss how the combination of novel experimental approaches with theoretical studies is currently utilized to unravel the molecular mechanisms governing mechano-chemical coupling during cell adhesion. Copyright 2017 The Authors. Published by Elsevier B.V. All rights reserved.

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Language(s): eng - English
 Dates: 2017-04-042017-12
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: ISI: 28389162
DOI: 10.1016/j.matbio.2017.03.004
 Degree: -

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Project name : European Research Council (Grant Agreement no. 322652)
Grant ID : 322652
Funding program : -
Funding organization : European Research Council

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Title: Matrix Biology
  Other : Matrix Biol.
Source Genre: Journal
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Publ. Info: Stuttgart : Elsevier
Pages: - Volume / Issue: 64 Sequence Number: - Start / End Page: 6 - 16 Identifier: ISSN: 0945-053X
CoNE: https://pure.mpg.de/cone/journals/resource/954927704149