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  Derivatisation of carboxyl groups of tobacco mosaic virus with cystamine

King, L., & Leberman, R. (1973). Derivatisation of carboxyl groups of tobacco mosaic virus with cystamine. Biochimica et Biophysica Acta: BBA, 322(2), 279-293. doi:10.1016/0005-2795(73)90304-8.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002D-DC40-9 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-002D-DC41-7
Genre: Journal Article

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BBA-ProteinStructure_322_1973_279.pdf (Any fulltext), 2MB
 
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 Creators:
King, L1, Author           
Leberman, R.1, Author           
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1Max Planck Institute for Medical Research, Max Planck Society, ou_1125545              

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 Abstract: The coupling of cystamine to carboxyl groups of tobacco mosaic virus mediated by a water-soluble carbodiimide has been studied. The purpose of this study was to provide further heavy atom derivatives for X-ray diffraction analysis of the virus. Although this was not achieved due to the insolubilisation of the virus during the reaction, it was found that the reaction is limited to essentially only 3 of the carboxyl groups of the virus protein subunits and is consistent with these sites being located towards the outside of the virus particle.

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Language(s): eng - English
 Dates: 2003-01-301973-10-18
 Publication Status: Issued
 Pages: 15
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/0005-2795(73)90304-8
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Title: Biochimica et Biophysica Acta : BBA
  Other : Biochimica et Biophysica Acta (BBA) - Biomembranes
Source Genre: Journal
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Publ. Info: Amsterdam : Elsevier
Pages: - Volume / Issue: 322 (2) Sequence Number: - Start / End Page: 279 - 293 Identifier: Other: 1879-2642
CoNE: https://pure.mpg.de/cone/journals/resource/18792642