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  Synthetic vaccines against Streptococcus pneumoniae serotype 2

Khan, N., & Emmadi, M.(2017). Synthetic vaccines against Streptococcus pneumoniae serotype 2.

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 Creators:
Seeberger, Peter H.1, Inventor           
Pereira, Claney Lebev2, Inventor           
Chakkumkal, Anish3, Inventor           
Khan, Naeem2, Author           
Emmadi, Madhu2, Author           
Affiliations:
1Peter H. Seeberger, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_2040285              
2Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863308              
3Chakkumal Anish, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863299              

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 Abstract: The present invention relates to a synthetic saccharide of general formula (I) that is related to Streptococcus pneumoniae serotype 2 capsular polysaccharide, a conjugate thereof and the use of said saccharide and conjugate for raising a protective immune response in a human and/or animal host. Furthermore, the synthetic saccharide of general formula (I) is useful as marker in immunological assays for detection of antibodies against Streptococcus pneumoniae type 2 bacteria. Another aspect of the present invention is directed to an antibody having specificity for a synthetic saccharide of general formula (I).

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 Dates: 2015-12-172017-06-21
 Publication Status: Published online
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 Identifiers: Patent Publication Nr.: EP3181148 A1
Patent Application Nr.: EP20150200729
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